支气管癌切除后的5年生存率。其预后的多因素分析]。

N Roeslin, D Grangé, E Roegel, J P Witz, G Morand, J M Wihlm, C Bohner, G Pauli, E Weitzenblum, A Warter
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引用次数: 0

摘要

支气管癌(燕麦细胞癌)手术患者的预后。通过两种统计方法比较存活5年及以上的178例患者(I组)和5年以内死亡的178例患者(II组),两组患者在同一时期接受过治疗。两组比较提示,以下因素是预后良好的指标:体重-身高比在正常范围内,近期无体重减轻,偶然发现癌;支气管镜检查的正常面;T1 N0型无血管扩张,活动受限。在第二组中通常观察到癌症复发,但在第一组中可能出现复发。肺转移和“新”支气管癌之间的鉴别预后很难。生存率最终取决于复发和转移的频率。通过相应的析因分析,可以区分和确定预后好、生存期长的患者和预后差、生存期短的患者的主要特征。然而,由于转移的发生通常是不可预测的,因此只有30%的病例是准确的。从这些数据来看,手术似乎只适用于一种肿瘤;T1:常规检查检出N0癌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[5-year survival of resected bronchial cancer. Multifactorial analysis of its prognosis].

Prognosis in patients having undergone surgery for a bronchial carcinoma (oat cell. carcinoma excluded) was studied by comparing, with two statistical methods, a group of 178 patients surviving five years and more (group I) and a group of 178 patients who died within five years (group II). The two groups had undergone treatment during the same period. Comparison of the two groups suggested that the following factors were indicators of a good prognosis: ratio weight-height within normal limits without recent weight loss, fortuitous detection of the carcinoma; normal aspect on bronchoscopy; T1 N0 type without vascular extension, limited exeresis. Recurrences of the carcinoma were generally observed in group II but could be present in group I. The differential prognosis between pulmonary metastases and a "new" bronchial carcinoma was difficult. Survival was finally determined by the frequency of recurrences and metastases. By a correspondences factorial analysis it was possible to separate and to define the main characteristics of the patients with a good prognosis and a long survival and of those with a poor prognosis and a short survival. However this proved to be exact in only 30% of the individual cases because occurrence of metastases was generally unforeseable. From these data it appears that surgery alone is indicated in only one kind of tumours; T1 N0 carcinomas detected by routine examinations.

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