[念珠菌EH 15/D突变体氨基酸合成的一般控制]。

R Bode, P Casper
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引用次数: 4

摘要

研究了念珠菌EH 15/D中氨基酸生物合成的一般控制,使用单突变和双突变的营养不良菌株和缺乏所需氨基酸的原营养复合体。这些实验表明,缺乏赖氨酸、组氨酸、精氨酸、亮氨酸、苏氨酸、脯氨酸、丝氨酸、蛋氨酸、同型丝氨酸、天冬酰胺、谷氨酸或天冬氨酸可导致酶的抑制。在抑制程度、菌株生长和所需氨基酸浓度之间发现了相关性。突变体和回变体的氨基酸库模式与野生型菌株不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[General control of amino acid biosynthesis in mutants of Candida spec. EH 15/D].

The general control of amino acid biosynthesis was investigated in Candida spec. EH 15/D, using single and double mutant auxotrophic strains and prototrophic revertants starved for their required amino acids. These experiments show that starvation for lysine, histidine, arginine, leucine, threonine, proline, serine, methionine, homoserine, asparagine, glutamic acid or aspartic acid can result in derepression of enzymes. A correlation was found between the degree of derepression, growth of strains, and concentration of required amino acids. The amino acids pool pattern of mutants and revertants is different from that in the wild type strain.

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