[工作环境中癌症风险的评估。流行病学方法)。

S Perdrizet
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引用次数: 0

摘要

对工作场所致癌风险的分析有两个基本步骤:首先是描述性方法,这可能引起人们对某种物质与疾病发生频率或死亡率有关的怀疑;然后是基于回顾性和前瞻性横断面研究的分析性方法。这些研究证明了致癌产品与肺癌发病率之间存在关系。这类研究的贡献越丰富,完成起来就越困难。所有这些研究都假定某些限制条件是可以接受的:一项精确的协议,收集正确的数据,选择必要时进行研究和控制的有关人口;对前瞻性研究中观察的每个队列进行严格监督,并对扭曲因素作出规定。这些研究的结果应该是避免职业性癌症,而不是在临床或放射学上明显时才发现它们。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Assessment of cancer risk in the work environment. Epidemiologic approach].

There are two essential steps in the analysis of carcinogenic risks in the work place: first, a descriptive approach which might raise the suspicion of an agent related to the frequency of a disease or mortality rate and then the analytical approach, based on retrospective and prospective cross-sectional studies. Such studies allow proof of the existence of a relation between a carcinogenic product and the frequency of lung cancer. The richer the contribution of such studies, the more difficult their accomplishment. All these studies assume that certain constraints are accepted: a precise protocol, collection of correct data, choice of a relevant population to be studied and controlled when necessary; rigorous supervision of each cohort under observation in the prospective studies, provision made for distorting factors. Such studies ought to result in averting occupational cancers rather than detecting them when clinically or radiologically apparent.

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