S C Gilman, J M Hallenbeck, M J Ackerman, M E Bradley
{"title":"牛磺酸对豚鼠压力性震颤的拮抗作用。","authors":"S C Gilman, J M Hallenbeck, M J Ackerman, M E Bradley","doi":"10.1152/jappl.1984.57.5.1409","DOIUrl":null,"url":null,"abstract":"<p><p>The tremorogenic effect of high pressure was antagonized in guinea pigs by intravenous treatment with taurine in doses of 250 and 500 mg/kg. Also pretreatment with 250 mg/kg taurine suppressed tremor development as evidenced by increased threshold and decreased amplitude. It is hypothesized that antagonism of pressure-induced tremor by taurine may be related to changes in membrane calcium transport.</p>","PeriodicalId":15258,"journal":{"name":"Journal of applied physiology: respiratory, environmental and exercise physiology","volume":"57 5","pages":"1409-11"},"PeriodicalIF":0.0000,"publicationDate":"1984-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/jappl.1984.57.5.1409","citationCount":"6","resultStr":"{\"title\":\"Antagonism by taurine of pressure-induced tremor in the guinea pig.\",\"authors\":\"S C Gilman, J M Hallenbeck, M J Ackerman, M E Bradley\",\"doi\":\"10.1152/jappl.1984.57.5.1409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The tremorogenic effect of high pressure was antagonized in guinea pigs by intravenous treatment with taurine in doses of 250 and 500 mg/kg. Also pretreatment with 250 mg/kg taurine suppressed tremor development as evidenced by increased threshold and decreased amplitude. It is hypothesized that antagonism of pressure-induced tremor by taurine may be related to changes in membrane calcium transport.</p>\",\"PeriodicalId\":15258,\"journal\":{\"name\":\"Journal of applied physiology: respiratory, environmental and exercise physiology\",\"volume\":\"57 5\",\"pages\":\"1409-11\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1152/jappl.1984.57.5.1409\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of applied physiology: respiratory, environmental and exercise physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1152/jappl.1984.57.5.1409\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of applied physiology: respiratory, environmental and exercise physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1152/jappl.1984.57.5.1409","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antagonism by taurine of pressure-induced tremor in the guinea pig.
The tremorogenic effect of high pressure was antagonized in guinea pigs by intravenous treatment with taurine in doses of 250 and 500 mg/kg. Also pretreatment with 250 mg/kg taurine suppressed tremor development as evidenced by increased threshold and decreased amplitude. It is hypothesized that antagonism of pressure-induced tremor by taurine may be related to changes in membrane calcium transport.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
