不同布鲁氏锥虫毒株感染小型猪的组织病理学观察。

Tropenmedizin und Parasitologie Pub Date : 1984-06-01
W Büngener, D Mehlitz
{"title":"不同布鲁氏锥虫毒株感染小型猪的组织病理学观察。","authors":"W Büngener,&nbsp;D Mehlitz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Two pigs infected with Trypanosoma brucei gambiense developed low parasitemia which became undetectable after 6 months; on autopsy 13 months after infection they showed no histopathological alterations. --Five of six pigs infected with a Trypanosoma brucei brucei strain from the Ivory Coast developed low parasitemia (up to about antilog 6.5 per ml of blood) which became progressively lower but was detectable up to one year after infection. On autopsy they showed interstitial myocarditis and meningo-encephalitis; during the course of the infection, the first became milder, the second more intense; no trypanosomes were seen in the tissues. One of these pigs developed a parasitemia of up to antilog 8 and died 172 days after infection from bacterial pneumonia, histologically it had severe myocarditis with many trypanosomes in the tissue and mild meningo-encephalitis. --Three pigs infected with a Trypanosoma brucei brucei strain from the Serengeti died 47, 68, 130 days after infection. The first dying pig had a high terminal parasitemia, in the others, the parasitemia was low until the end, being only detectable by the hematocrit centrifugation technique or by mouse passage. At autopsy, all showed massive myocarditis and interstitial nephritis with masses of extravascular trypanosomes, moderate meningo-encephalitis with very few trypanosomes, and widespread colonization of other organs and tissues by trypanosomes, still without marked cellular infiltrations.</p>","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"35 2","pages":"109-14"},"PeriodicalIF":0.0000,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Histopathological findings in mini-pigs infected with different strains of Trypanosoma brucei.\",\"authors\":\"W Büngener,&nbsp;D Mehlitz\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Two pigs infected with Trypanosoma brucei gambiense developed low parasitemia which became undetectable after 6 months; on autopsy 13 months after infection they showed no histopathological alterations. --Five of six pigs infected with a Trypanosoma brucei brucei strain from the Ivory Coast developed low parasitemia (up to about antilog 6.5 per ml of blood) which became progressively lower but was detectable up to one year after infection. On autopsy they showed interstitial myocarditis and meningo-encephalitis; during the course of the infection, the first became milder, the second more intense; no trypanosomes were seen in the tissues. One of these pigs developed a parasitemia of up to antilog 8 and died 172 days after infection from bacterial pneumonia, histologically it had severe myocarditis with many trypanosomes in the tissue and mild meningo-encephalitis. --Three pigs infected with a Trypanosoma brucei brucei strain from the Serengeti died 47, 68, 130 days after infection. The first dying pig had a high terminal parasitemia, in the others, the parasitemia was low until the end, being only detectable by the hematocrit centrifugation technique or by mouse passage. At autopsy, all showed massive myocarditis and interstitial nephritis with masses of extravascular trypanosomes, moderate meningo-encephalitis with very few trypanosomes, and widespread colonization of other organs and tissues by trypanosomes, still without marked cellular infiltrations.</p>\",\"PeriodicalId\":76764,\"journal\":{\"name\":\"Tropenmedizin und Parasitologie\",\"volume\":\"35 2\",\"pages\":\"109-14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tropenmedizin und Parasitologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tropenmedizin und Parasitologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

感染布氏冈比亚锥虫的两头猪出现低寄生虫病,6个月后无法检测到;在感染13个月后的尸检中,他们没有发现任何组织病理学改变。感染了来自科特迪瓦的布氏锥虫菌株的6头猪中有5头出现了低寄生虫血症(高达每毫升血液约6.5安提洛格),这一水平逐渐降低,但在感染一年后仍可检测到。尸检显示为间质性心肌炎和脑膜脑炎;在感染过程中,第一种变得较轻,第二种变得更强烈;组织中未见锥虫。其中一头猪出现了高达antilog8的寄生虫血症,在感染细菌性肺炎172天后死亡,组织学上有严重的心肌炎,组织中有许多锥虫,轻度脑膜脑炎。——三只感染了来自塞伦盖蒂的布氏锥虫菌株的猪在感染后47、68和130天死亡。第1只死猪终末寄生率高,其余死猪终末寄生率低,只能通过血细胞比容离心技术或小鼠传代检测到。尸检时,所有患者均表现为大量心肌炎和间质性肾炎伴大量血管外锥虫,中度脑膜脑炎伴极少锥虫,锥虫在其他器官和组织中广泛定植,但未见明显的细胞浸润。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Histopathological findings in mini-pigs infected with different strains of Trypanosoma brucei.

Two pigs infected with Trypanosoma brucei gambiense developed low parasitemia which became undetectable after 6 months; on autopsy 13 months after infection they showed no histopathological alterations. --Five of six pigs infected with a Trypanosoma brucei brucei strain from the Ivory Coast developed low parasitemia (up to about antilog 6.5 per ml of blood) which became progressively lower but was detectable up to one year after infection. On autopsy they showed interstitial myocarditis and meningo-encephalitis; during the course of the infection, the first became milder, the second more intense; no trypanosomes were seen in the tissues. One of these pigs developed a parasitemia of up to antilog 8 and died 172 days after infection from bacterial pneumonia, histologically it had severe myocarditis with many trypanosomes in the tissue and mild meningo-encephalitis. --Three pigs infected with a Trypanosoma brucei brucei strain from the Serengeti died 47, 68, 130 days after infection. The first dying pig had a high terminal parasitemia, in the others, the parasitemia was low until the end, being only detectable by the hematocrit centrifugation technique or by mouse passage. At autopsy, all showed massive myocarditis and interstitial nephritis with masses of extravascular trypanosomes, moderate meningo-encephalitis with very few trypanosomes, and widespread colonization of other organs and tissues by trypanosomes, still without marked cellular infiltrations.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信