{"title":"[Sulfentanil柠檬酸。清醒者肌内注射的管理[作者简介]。","authors":"M Cathelin, R Vignes, A Malki, P Viars","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In the case of a conscious man suffering from a painful injury in the facial and trigeminal nerves, the administration of intra-muscular injections of increasing doses of morphine and sulfentanil provokes constant analgesia in direct proportion to the administered dose. The admitted dosages for each product are as follows. M = 0,100, 0,150, 0,200 mg/kg S = 0,00015, 0,0003, 0,0006 mg/kg. Sulfentanil is a highly active analgesic whose activity is about 333 times greater than that of morphine and 13 times greater than that of fentanyl. In the case of each of the 3 products, the point at which analgesia becomes clinically discernable is the same. Optimum intensity of action of the analgesia is arrived at in all 3 cases within a period of 60 to 90 minutes. The higher the dose administered, the longer sulfentanil can be expected to work. Although effective for a shorter period of time than morphine and fentanyl sulfentanil effectiveness is too great for it to be considered a short-acting analgesic.</p>","PeriodicalId":7785,"journal":{"name":"Anesthesie, analgesie, reanimation","volume":"38 1-2","pages":"21-5"},"PeriodicalIF":0.0000,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Sulfentanil citrate. Administration of intramuscular injections in conscious man (author's transl)].\",\"authors\":\"M Cathelin, R Vignes, A Malki, P Viars\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In the case of a conscious man suffering from a painful injury in the facial and trigeminal nerves, the administration of intra-muscular injections of increasing doses of morphine and sulfentanil provokes constant analgesia in direct proportion to the administered dose. The admitted dosages for each product are as follows. M = 0,100, 0,150, 0,200 mg/kg S = 0,00015, 0,0003, 0,0006 mg/kg. Sulfentanil is a highly active analgesic whose activity is about 333 times greater than that of morphine and 13 times greater than that of fentanyl. In the case of each of the 3 products, the point at which analgesia becomes clinically discernable is the same. Optimum intensity of action of the analgesia is arrived at in all 3 cases within a period of 60 to 90 minutes. The higher the dose administered, the longer sulfentanil can be expected to work. Although effective for a shorter period of time than morphine and fentanyl sulfentanil effectiveness is too great for it to be considered a short-acting analgesic.</p>\",\"PeriodicalId\":7785,\"journal\":{\"name\":\"Anesthesie, analgesie, reanimation\",\"volume\":\"38 1-2\",\"pages\":\"21-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anesthesie, analgesie, reanimation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anesthesie, analgesie, reanimation","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Sulfentanil citrate. Administration of intramuscular injections in conscious man (author's transl)].
In the case of a conscious man suffering from a painful injury in the facial and trigeminal nerves, the administration of intra-muscular injections of increasing doses of morphine and sulfentanil provokes constant analgesia in direct proportion to the administered dose. The admitted dosages for each product are as follows. M = 0,100, 0,150, 0,200 mg/kg S = 0,00015, 0,0003, 0,0006 mg/kg. Sulfentanil is a highly active analgesic whose activity is about 333 times greater than that of morphine and 13 times greater than that of fentanyl. In the case of each of the 3 products, the point at which analgesia becomes clinically discernable is the same. Optimum intensity of action of the analgesia is arrived at in all 3 cases within a period of 60 to 90 minutes. The higher the dose administered, the longer sulfentanil can be expected to work. Although effective for a shorter period of time than morphine and fentanyl sulfentanil effectiveness is too great for it to be considered a short-acting analgesic.