{"title":"定量测定大C3片段作为小鼠补体活化的指标。2体内研究。","authors":"J Lulé, G J Fournié, J J Conté","doi":"10.1159/000467822","DOIUrl":null,"url":null,"abstract":"<p><p>A method which enables to evaluate the mouse C3 activation has been used to study the activation of the complement system in C57Bl/6 mice injected with cobra venom factor, with Escherichia coli, and with bacterial lipopolysaccharide. It was found that this method was able to detect the complement activation early, at a time when total levels of C3-reacting molecules had not yet decreased.</p>","PeriodicalId":77697,"journal":{"name":"Complement (Basel, Switzerland)","volume":"1 2","pages":"103-7"},"PeriodicalIF":0.0000,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000467822","citationCount":"0","resultStr":"{\"title\":\"Quantification of large C3 fragments as an index of complement activation in mice. II. In vivo studies.\",\"authors\":\"J Lulé, G J Fournié, J J Conté\",\"doi\":\"10.1159/000467822\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A method which enables to evaluate the mouse C3 activation has been used to study the activation of the complement system in C57Bl/6 mice injected with cobra venom factor, with Escherichia coli, and with bacterial lipopolysaccharide. It was found that this method was able to detect the complement activation early, at a time when total levels of C3-reacting molecules had not yet decreased.</p>\",\"PeriodicalId\":77697,\"journal\":{\"name\":\"Complement (Basel, Switzerland)\",\"volume\":\"1 2\",\"pages\":\"103-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000467822\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Complement (Basel, Switzerland)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000467822\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Complement (Basel, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000467822","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Quantification of large C3 fragments as an index of complement activation in mice. II. In vivo studies.
A method which enables to evaluate the mouse C3 activation has been used to study the activation of the complement system in C57Bl/6 mice injected with cobra venom factor, with Escherichia coli, and with bacterial lipopolysaccharide. It was found that this method was able to detect the complement activation early, at a time when total levels of C3-reacting molecules had not yet decreased.