R L Bratcher, C L Kanik-Ennulat, P J Logue, P B Dunham
{"title":"免疫球蛋白片段对LK羊红细胞钠钾泵的刺激作用。","authors":"R L Bratcher, C L Kanik-Ennulat, P J Logue, P B Dunham","doi":"10.3109/08820138309025438","DOIUrl":null,"url":null,"abstract":"<p><p>Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments, Fab1, of anti-L, as well as dimeric fragments, F(ab1)2, stimulate transport to the same extent as intact anti-L Ig. Special care was taken to obtain pure fragments. Two earlier reports on the effect of immunoglobulin fragments were contradictory.</p>","PeriodicalId":13417,"journal":{"name":"Immunological communications","volume":"12 6","pages":"565-71"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08820138309025438","citationCount":"3","resultStr":"{\"title\":\"Stimulation of the Na/K pump in LK sheep erythrocytes by immunoglobulin fragments.\",\"authors\":\"R L Bratcher, C L Kanik-Ennulat, P J Logue, P B Dunham\",\"doi\":\"10.3109/08820138309025438\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments, Fab1, of anti-L, as well as dimeric fragments, F(ab1)2, stimulate transport to the same extent as intact anti-L Ig. Special care was taken to obtain pure fragments. Two earlier reports on the effect of immunoglobulin fragments were contradictory.</p>\",\"PeriodicalId\":13417,\"journal\":{\"name\":\"Immunological communications\",\"volume\":\"12 6\",\"pages\":\"565-71\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/08820138309025438\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunological communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/08820138309025438\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunological communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08820138309025438","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Stimulation of the Na/K pump in LK sheep erythrocytes by immunoglobulin fragments.
Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments, Fab1, of anti-L, as well as dimeric fragments, F(ab1)2, stimulate transport to the same extent as intact anti-L Ig. Special care was taken to obtain pure fragments. Two earlier reports on the effect of immunoglobulin fragments were contradictory.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
