[人巨细胞病毒单克隆抗体的制备]。

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1983-01-01

M C Mazeron, T Berbar, M C Guillemin, R Colimon, A Roseto, Y Perol

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引用次数: 0

摘要

Sp2/0(一种来源于小鼠骨髓瘤的非分泌性变异)与免疫人类巨细胞病毒的小鼠脾淋巴细胞的细胞融合，产生了两个稳定的杂交瘤，产生单克隆抗体(IgG)，与感染周期早期出现的抗原特异性反应，并保留在细胞核中。

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[Production of monoclonal antibodies against human cytomegalovirus].

Cell fusion of Sp2/0, a murine myeloma derived non-secreting variant, with splenic lymphocytes from Mice immunized against human cytomegalovirus, has originated two stable hybridomas producing monoclonal antibodies (IgG) which react specifically with antigens that appear early in infectious cycle and remain localized in the cell nucleus.

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Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie

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