[阻断受HLA-DR7或HLA-DR1分子或未知分子限制的克隆细胞系的抗流感特异性增殖反应]。

G Sterkers, C Hannoun, J P Lévy
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引用次数: 0

摘要

描述了四种不同的T淋巴细胞连续细胞系,其中三种是通过克隆获得的。它们的活性在三个病例中受到组织相容性抗原与HLA-DR无法区分的限制。最后一个被一个自身的未识别结构所限制。前三条系对H3血凝素亚型对应的病毒抗原具有特异性。第四条线似乎与A型和B型流感病毒共有的一种迄今尚未描述的抗原发生反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Blockade of the anti-influenza specific proliferative response of cloned cell lines restricted either by HLA-DR7 or HLA-DR1 molecules or by a still-unknown molecule].

Four different continuous cell lines of T lymphocytes are described, three of them were obtained by cloning. Their activity is restricted in three cases by a histocompatibility antigen undistinguishable from HLA-DR. The last one is restricted by an autologous unidentified structure. The first three lines are specific for a viral antigen corresponding to a subtype of the H3 hemagglutinin. The fourth line seems to react with an hitherto undescribed antigen shared by type A and type B influenza viruses.

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