Y Pennec, C Ferrec, P Youinou, J Colin, D Mottier, J Jouquan, P Miossec, G Le Menn
{"title":"[Gougerot-Sjögren综合征患者唾液溶菌酶、免疫球蛋白和β 2微球蛋白]。","authors":"Y Pennec, C Ferrec, P Youinou, J Colin, D Mottier, J Jouquan, P Miossec, G Le Menn","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Lysozyme (LZM), immunoglobulins and beta 2-microglobulin concentrations were measured in the saliva of 79 patients with primary (n = 29) or secondary (n = 50) Sjögren's syndrome and in a control population. beta 2-microglobulin and immunoglobulins A, G and M concentrations were higher, and LZM concentrations lower than in controls. A significant correlation was established between LZM and immunoglobulins, but no correlation was found between immunoglobulins and beta 2-microglobulin, nor between the latter and LZM. These results indicate that salivary LZM concentration may be of value in the diagnosis of Sjögren's syndrome.</p>","PeriodicalId":17974,"journal":{"name":"La Nouvelle presse medicale","volume":"11 47","pages":"3481-4"},"PeriodicalIF":0.0000,"publicationDate":"1982-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Salivary lysozyme, immunoglobulins and beta 2-microglobulin in Gougerot-Sjögren syndrome].\",\"authors\":\"Y Pennec, C Ferrec, P Youinou, J Colin, D Mottier, J Jouquan, P Miossec, G Le Menn\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Lysozyme (LZM), immunoglobulins and beta 2-microglobulin concentrations were measured in the saliva of 79 patients with primary (n = 29) or secondary (n = 50) Sjögren's syndrome and in a control population. beta 2-microglobulin and immunoglobulins A, G and M concentrations were higher, and LZM concentrations lower than in controls. A significant correlation was established between LZM and immunoglobulins, but no correlation was found between immunoglobulins and beta 2-microglobulin, nor between the latter and LZM. These results indicate that salivary LZM concentration may be of value in the diagnosis of Sjögren's syndrome.</p>\",\"PeriodicalId\":17974,\"journal\":{\"name\":\"La Nouvelle presse medicale\",\"volume\":\"11 47\",\"pages\":\"3481-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"La Nouvelle presse medicale\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"La Nouvelle presse medicale","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Salivary lysozyme, immunoglobulins and beta 2-microglobulin in Gougerot-Sjögren syndrome].
Lysozyme (LZM), immunoglobulins and beta 2-microglobulin concentrations were measured in the saliva of 79 patients with primary (n = 29) or secondary (n = 50) Sjögren's syndrome and in a control population. beta 2-microglobulin and immunoglobulins A, G and M concentrations were higher, and LZM concentrations lower than in controls. A significant correlation was established between LZM and immunoglobulins, but no correlation was found between immunoglobulins and beta 2-microglobulin, nor between the latter and LZM. These results indicate that salivary LZM concentration may be of value in the diagnosis of Sjögren's syndrome.
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