{"title":"非洲伯基特瘤、鼻咽癌及对照组血清β -2微球蛋白。","authors":"E H Cooper, S M Kerruish, P Gunvèn","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Serum beta2-microglobulin measurements were made in Burkitt lymphoma and nasopharyngeal carcinoma in Africans and infectious mononucleosis in Europeans. There was a significant increase of beta2-microglobulin levels in active Burkitt tumour compared to those in remission but young West African children have higher levels than that in Caucasians. Nasopharyngeal carcinoma can be associated with a raised beta2-microglobulin but the distribution is similar to that seen in other head and neck cancers. In 27 cases of infectious mononucleosis 74% have raised levels of serum beta2-microglobulin. The mechanism of production of high serum beta2-microglobulin levels in rural African children is as yet unknown.</p>","PeriodicalId":9217,"journal":{"name":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","volume":"35 3","pages":"104-7"},"PeriodicalIF":0.0000,"publicationDate":"1981-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Serum beta-2-microglobulin in African Burkitt tumour, nasopharyngeal carcinoma and controls.\",\"authors\":\"E H Cooper, S M Kerruish, P Gunvèn\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Serum beta2-microglobulin measurements were made in Burkitt lymphoma and nasopharyngeal carcinoma in Africans and infectious mononucleosis in Europeans. There was a significant increase of beta2-microglobulin levels in active Burkitt tumour compared to those in remission but young West African children have higher levels than that in Caucasians. Nasopharyngeal carcinoma can be associated with a raised beta2-microglobulin but the distribution is similar to that seen in other head and neck cancers. In 27 cases of infectious mononucleosis 74% have raised levels of serum beta2-microglobulin. The mechanism of production of high serum beta2-microglobulin levels in rural African children is as yet unknown.</p>\",\"PeriodicalId\":9217,\"journal\":{\"name\":\"Biomedicine / [publiee pour l'A.A.I.C.I.G.]\",\"volume\":\"35 3\",\"pages\":\"104-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedicine / [publiee pour l'A.A.I.C.I.G.]\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedicine / [publiee pour l'A.A.I.C.I.G.]","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Serum beta-2-microglobulin in African Burkitt tumour, nasopharyngeal carcinoma and controls.
Serum beta2-microglobulin measurements were made in Burkitt lymphoma and nasopharyngeal carcinoma in Africans and infectious mononucleosis in Europeans. There was a significant increase of beta2-microglobulin levels in active Burkitt tumour compared to those in remission but young West African children have higher levels than that in Caucasians. Nasopharyngeal carcinoma can be associated with a raised beta2-microglobulin but the distribution is similar to that seen in other head and neck cancers. In 27 cases of infectious mononucleosis 74% have raised levels of serum beta2-microglobulin. The mechanism of production of high serum beta2-microglobulin levels in rural African children is as yet unknown.
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