[尸体细菌学检查下梭状芽孢杆菌对谷氨酸和脯氨酸的降解]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1984-10-01

W Huckenbeck, T Daldrup

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引用次数: 0

摘要

从腐烂的人脑中分离出的梭氏梭状芽胞杆菌将谷氨酸(GLU)脱羧为γ -氨基丁酸(GABA)。确定了该反应与温度、pH和底物浓度的关系。ph值的最优值为5.0 ~ 5.2。在接近最佳pH值时，最佳温度大于28℃。在较高的pH值(6 ~ 7)下，活性相对独立于温度。这与人类大脑腐烂的结果相似(10,11,12)，表明死后细菌菌群与葡萄糖降解之间存在良好的相关性。此外，sordellii还能从脯氨酸(PRO)中产生delta- aminvaleric酸(AVA)。

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[Degradation of glutamic acid and proline in Clostridium sordellii under cadaveric bacteriological inspection].

Glutamic acid (GLU) is decarboxylated to gamma-aminobutyric acid (GABA) by Clostridium sordellii isolated from a decaying human brain. The dependence of this reaction on temperature, pH and substrate concentration has been established. The pH-optimum is in the range of 5.0 to 5.2. Near optimal pH the temperature optimum is greater than 28 degrees C. At higher pH-values (6 to 7) activity is relatively independent of temperature. The similarity to results in decaying human brains (10, 11, 12) shows a good correlation between postmortem bacterial flora and GLU-degradation. Furthermore it is shown that C. sordellii produces delta-aminovaleric acid (AVA) from proline (PRO).

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Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology

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