大黄蜂毒液对心脏的影响。

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology Pub Date : 1983-01-01

T Abe, N Kawai

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引用次数: 0

摘要

在心电图实验中，大黄蜂粗毒液对大鼠心脏有明显的促心作用。腹腔注射毒液后5min内心率加快，随后心跳受阻，导致传导延迟。通过凝胶过滤将心脏活性成分分离成两种成分。一种是蛋白质等高分子物质，表现为完全房室传导阻滞。另一种分子量较低的成分被分成5个峰，从而加速了心率。

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Cardioactive effects of hornet venom, Vespa mandarinia.

In the experiment of electrocardiogram, the crude venom of giant hornet (Vespa mandarinia) showed cardioactive effects on rat heart. The heart rate was accelerated within 5 min after injection of the venom intraperitoneally, then the heart beat was blocked, resulting in conduction delay. The cardioactive constituent was separated into two components by gel filtration. One which was high molecular species such as protein showed complete atrioventricular block. Another component, having a low molecular weight, was fractionated in 5 peaks, which accelerated heart rate.

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Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology

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