人I型t细胞白血病病毒独特序列pX编码蛋白p40x的鉴定

Gan Pub Date : 1984-09-01

T Kiyokawa, M Seiki, K Imagawa, F Shimizu, M Yoshida

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引用次数: 0

摘要

在i型人t细胞白血病病毒的pX区鉴定出一种蛋白p40x，该蛋白是由frame IV编码的产物。成人t细胞白血病患者血清中含有针对p40x的抗体，表明其在体内表达。提出了剪接形成pX mRNA的发生，并讨论了p40x可能的意义。

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Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I.

A protein p40x was identified as a product encoded by frame IV in the pX region of human T-cell leukemia virus type I. Sera from patients with adult T-cell leukemia contained antibodies against p40x, indicating its expression in vivo. The occurrence of splicing to form pX mRNA is proposed and the possible significance of p40x is discussed.

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Gan

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