成人t细胞白血病患者外周血含t细胞白血病病毒b细胞系的建立和鉴定。

Gan Pub Date : 1984-08-01

K Miyamoto, N Tomita, A Ishii, T Nishizaki, A Togawa

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引用次数: 0

摘要

从7例成人t细胞白血病(ATL)患者中分别建立了以表面IgA kappa免疫球蛋白为主的b细胞系。在其中5个品系中发现了ATL病毒原病毒DNA。虽然b细胞系的染色体分析结果正常，但新鲜的白血病t细胞显示染色体异常。

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Establishment and characterization of adult T-cell leukemia virus-containing B-cell lines derived from peripheral blood of adult T-cell leukemia patients.

B-cell lines which showed predominantly surface IgA kappa immunoglobulins were established from each of seven adult T-cell leukemia (ATL) patients. ATL virus proviral DNA was found in five of the lines. Though the chromosomal analysis of the B-cell lines yielded normal results, fresh leukemic T-cells showed chromosome abnormalities.

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Gan

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