Hypolipoproteinaemia.

Hypolipoproteinaemia, resulting from deficiency of one or more of the major serum lipoprotein fractions, may be due to a primary genetically determined condition or may occur as a secondary manifestation in another disease state (table I). This paper will be confined to a discussion of the primary disorders which, although rare, have contributed greatly to our understanding of the normal function of the serum lipoproteins.