47万道尔顿抗原复合物和过氧化氢酶抗原在烟曲霉临床分离株中的变异。

H Schønheyder, L Storgaard, P Andersen
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引用次数: 12

摘要

采用免疫电泳法对18株曲霉断裂菌丝体抗原进行了研究,其中包括14株烟曲霉临床分离株。在所有烟曲霉分离株中均检测到分子量为470000的抗原成分和具有过氧化氢酶活性的抗原成分,但含量不同。470000抗原复合物与黄曲霉和灰曲霉抗原发生交叉反应,而与黑曲霉和地曲霉抗原不发生交叉反应。烟曲霉过氧化氢酶抗原在黄曲霉、灰曲霉和地曲霉中与过氧化氢酶发生交叉反应,而在黑曲霉中不发生交叉反应。一株烟曲霉分离物产生两种过氧化氢酶抗原,表现出部分同一性反应。黄曲霉也产生两种过氧化氢酶抗原,其中一种是种特异性的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Variation of a 470 000 daltons antigen complex and catalase antigen in clinical isolates of Aspergillus fumigatus.

Antigens in ruptured mycelium of 18 Aspergillus strains including 14 clinical isolates of A. fumigatus were studied by immunoelectrophoresis. One antigenic component of molecular weight 470 000 previously characterized by hydrophobic interaction chromatography and gel filtration and a second component with catalase activity were detected in all A. fumigatus isolates but in varying quantities. The 470 000 antigen complex cross-reacted with antigens in A. flavus and A. nidulans but not in A. niger or A. terreus. A. fumigatus catalase antigen cross-reacted with catalase in A. flavus, A. nidulans and A. terreus, but not in A. niger. One A. fumigatus isolate produced two catalase antigens showing a reaction of partial identity. A. flavus also produced two catalase antigens, one of which was species-specific.

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