{"title":"血清在整个妊娠期和分娩时的促生长活性:通过三种不同的生物测定法进行评估。","authors":"M Bozzola, J Charrier, R M Schimpff","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Somatomedin evolution has been studied by employing three different bioassays in 181 pregnant women from the 7th week of gestation to delivery and in 18 women during the course of labor. In 105 additional mothers of full-term or pre-term neonates a significant increase of a serum growth-promoting activity (thymidine activity) was observed at delivery, as compared to nonpregnant controls, with a progressive return to normal levels in the post-partum period. Different results were found according to the assay method used, suggesting the multiplicity of growth factors and specific adaptations related to the stages of pregnancy.</p>","PeriodicalId":77679,"journal":{"name":"Biological research in pregnancy and perinatology","volume":"6 3","pages":"137-40"},"PeriodicalIF":0.0000,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Growth-promoting activity of serum throughout pregnancy and at delivery: evaluation by three different bioassays.\",\"authors\":\"M Bozzola, J Charrier, R M Schimpff\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Somatomedin evolution has been studied by employing three different bioassays in 181 pregnant women from the 7th week of gestation to delivery and in 18 women during the course of labor. In 105 additional mothers of full-term or pre-term neonates a significant increase of a serum growth-promoting activity (thymidine activity) was observed at delivery, as compared to nonpregnant controls, with a progressive return to normal levels in the post-partum period. Different results were found according to the assay method used, suggesting the multiplicity of growth factors and specific adaptations related to the stages of pregnancy.</p>\",\"PeriodicalId\":77679,\"journal\":{\"name\":\"Biological research in pregnancy and perinatology\",\"volume\":\"6 3\",\"pages\":\"137-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biological research in pregnancy and perinatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biological research in pregnancy and perinatology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Growth-promoting activity of serum throughout pregnancy and at delivery: evaluation by three different bioassays.
Somatomedin evolution has been studied by employing three different bioassays in 181 pregnant women from the 7th week of gestation to delivery and in 18 women during the course of labor. In 105 additional mothers of full-term or pre-term neonates a significant increase of a serum growth-promoting activity (thymidine activity) was observed at delivery, as compared to nonpregnant controls, with a progressive return to normal levels in the post-partum period. Different results were found according to the assay method used, suggesting the multiplicity of growth factors and specific adaptations related to the stages of pregnancy.
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