DermL2V:通过llm驱动编码统一异质皮肤病学文本。

IF 7.7 2区 医学 Q1 COMPUTER SCIENCE, INFORMATION SYSTEMS
Bowen Guo, Jie Xu, Chen Ma, Zeju Li, Yuanyuan Wang, Yi Guo
{"title":"DermL2V:通过llm驱动编码统一异质皮肤病学文本。","authors":"Bowen Guo, Jie Xu, Chen Ma, Zeju Li, Yuanyuan Wang, Yi Guo","doi":"10.1109/JBHI.2026.3740718","DOIUrl":null,"url":null,"abstract":"<p><p>Dermatology diagnosis requires text encoding models that map unstructured descriptions to clinical semantic representations. Using public dermatology corpora to train such models remains highly challenging due to the lack of a specialized dataset offering unified semantic triplets as well as the difficulty of adaptively weighting clinically informative tokens and enhancing discrimination between clinically different but lexically similar descriptions. In this paper, we first construct DermSCL, a dermatology-specific dataset that organizes heterogeneous dermatology texts into 140,278 structured anchor-positive-negative semantic triplets and provides a unified supervision signal for text representation learning. Pretrained on DermSCL, we propose DermL2V, an LLM-based dermatology text encoder that improves representations by adaptively aggregating clinically relevant token information within a text and distinguishing semantic differences across different texts. First, we introduce a novel Clinical-Aware Relevance Aggregation module, where multiple relevance heads learn complementary token-level relevance patterns under dermatology-specific contrastive supervision to strengthen the representation. Second, we design a Boundary-Aware Semantic Mixup Strategy, which constructs intra- and inter-triplet near-boundary supervisory signals to enhance discrimination between clinically distinct yet lexically similar descriptions. Together, these two components synergistically improve the semantic robustness and discriminative capacity of the learned representations for dermatology. Furthermore, we evaluate DermL2V on important clinical tasks, including dermatology knowledge retrieval, embedding space analysis, concept classification and cross-modal retrieval. Across four out-of-domain dermatology retrieval datasets, DermL2V achieves the best average NDCG@10 and Recall@10 scores while delivering the best performance on the other downstream tasks. These results show DermL2V's potential as a dermatology-specific semantic encoder, providing reliable representations for retrieval-centered clinical applications. The project source code is publicly available here.</p>","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":7.7000,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"DermL2V: Unifying Heterogeneous Dermatology Texts Via LLM-Driven Encoding.\",\"authors\":\"Bowen Guo, Jie Xu, Chen Ma, Zeju Li, Yuanyuan Wang, Yi Guo\",\"doi\":\"10.1109/JBHI.2026.3740718\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Dermatology diagnosis requires text encoding models that map unstructured descriptions to clinical semantic representations. Using public dermatology corpora to train such models remains highly challenging due to the lack of a specialized dataset offering unified semantic triplets as well as the difficulty of adaptively weighting clinically informative tokens and enhancing discrimination between clinically different but lexically similar descriptions. In this paper, we first construct DermSCL, a dermatology-specific dataset that organizes heterogeneous dermatology texts into 140,278 structured anchor-positive-negative semantic triplets and provides a unified supervision signal for text representation learning. Pretrained on DermSCL, we propose DermL2V, an LLM-based dermatology text encoder that improves representations by adaptively aggregating clinically relevant token information within a text and distinguishing semantic differences across different texts. First, we introduce a novel Clinical-Aware Relevance Aggregation module, where multiple relevance heads learn complementary token-level relevance patterns under dermatology-specific contrastive supervision to strengthen the representation. Second, we design a Boundary-Aware Semantic Mixup Strategy, which constructs intra- and inter-triplet near-boundary supervisory signals to enhance discrimination between clinically distinct yet lexically similar descriptions. Together, these two components synergistically improve the semantic robustness and discriminative capacity of the learned representations for dermatology. Furthermore, we evaluate DermL2V on important clinical tasks, including dermatology knowledge retrieval, embedding space analysis, concept classification and cross-modal retrieval. Across four out-of-domain dermatology retrieval datasets, DermL2V achieves the best average NDCG@10 and Recall@10 scores while delivering the best performance on the other downstream tasks. These results show DermL2V's potential as a dermatology-specific semantic encoder, providing reliable representations for retrieval-centered clinical applications. The project source code is publicly available here.</p>\",\"PeriodicalId\":13073,\"journal\":{\"name\":\"IEEE Journal of Biomedical and Health Informatics\",\"volume\":\"PP \",\"pages\":\"\"},\"PeriodicalIF\":7.7000,\"publicationDate\":\"2026-10-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Journal of Biomedical and Health Informatics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1109/JBHI.2026.3740718\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"COMPUTER SCIENCE, INFORMATION SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Journal of Biomedical and Health Informatics","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1109/JBHI.2026.3740718","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

皮肤病诊断需要将非结构化描述映射到临床语义表示的文本编码模型。由于缺乏提供统一语义三元组的专门数据集,以及难以自适应地加权临床信息标记和增强临床不同但词汇相似的描述之间的区分,使用公共皮肤病学语料库来训练此类模型仍然具有很大的挑战性。在本文中,我们首先构建了皮肤病专用数据集DermSCL,该数据集将异构皮肤病文本组织为140278个结构化的锚定-正-负语义三元组,并为文本表示学习提供统一的监督信号。在对DermSCL进行预训练后,我们提出了DermL2V,这是一种基于法学硕士的皮肤医学文本编码器,它通过自适应地聚合文本内的临床相关标记信息并区分不同文本之间的语义差异来改进表示。首先,我们引入了一种新的临床感知相关聚合模块,在该模块中,多个相关头在特定皮肤科的对比监督下学习互补的令牌级相关模式,以加强表征。其次,我们设计了一个边界感知语义混淆策略,该策略构建了三联体内和三联体间的近边界监督信号,以增强临床不同但词汇相似的描述之间的区分。这两个组成部分协同提高了皮肤病学学习表征的语义鲁棒性和判别能力。此外,我们评估了DermL2V在皮肤科知识检索、嵌入空间分析、概念分类和跨模态检索等重要临床任务上的表现。在四个域外皮肤病学检索数据集中,DermL2V达到了最佳的平均NDCG@10和Recall@10分数,同时在其他下游任务上提供了最佳性能。这些结果显示了DermL2V作为皮肤病特定语义编码器的潜力,为以检索为中心的临床应用提供可靠的表示。项目源代码在这里公开提供。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DermL2V: Unifying Heterogeneous Dermatology Texts Via LLM-Driven Encoding.

Dermatology diagnosis requires text encoding models that map unstructured descriptions to clinical semantic representations. Using public dermatology corpora to train such models remains highly challenging due to the lack of a specialized dataset offering unified semantic triplets as well as the difficulty of adaptively weighting clinically informative tokens and enhancing discrimination between clinically different but lexically similar descriptions. In this paper, we first construct DermSCL, a dermatology-specific dataset that organizes heterogeneous dermatology texts into 140,278 structured anchor-positive-negative semantic triplets and provides a unified supervision signal for text representation learning. Pretrained on DermSCL, we propose DermL2V, an LLM-based dermatology text encoder that improves representations by adaptively aggregating clinically relevant token information within a text and distinguishing semantic differences across different texts. First, we introduce a novel Clinical-Aware Relevance Aggregation module, where multiple relevance heads learn complementary token-level relevance patterns under dermatology-specific contrastive supervision to strengthen the representation. Second, we design a Boundary-Aware Semantic Mixup Strategy, which constructs intra- and inter-triplet near-boundary supervisory signals to enhance discrimination between clinically distinct yet lexically similar descriptions. Together, these two components synergistically improve the semantic robustness and discriminative capacity of the learned representations for dermatology. Furthermore, we evaluate DermL2V on important clinical tasks, including dermatology knowledge retrieval, embedding space analysis, concept classification and cross-modal retrieval. Across four out-of-domain dermatology retrieval datasets, DermL2V achieves the best average NDCG@10 and Recall@10 scores while delivering the best performance on the other downstream tasks. These results show DermL2V's potential as a dermatology-specific semantic encoder, providing reliable representations for retrieval-centered clinical applications. The project source code is publicly available here.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
IEEE Journal of Biomedical and Health Informatics
IEEE Journal of Biomedical and Health Informatics COMPUTER SCIENCE, INFORMATION SYSTEMS-COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
CiteScore
13.60
自引率
6.50%
发文量
1151
期刊介绍: IEEE Journal of Biomedical and Health Informatics publishes original papers presenting recent advances where information and communication technologies intersect with health, healthcare, life sciences, and biomedicine. Topics include acquisition, transmission, storage, retrieval, management, and analysis of biomedical and health information. The journal covers applications of information technologies in healthcare, patient monitoring, preventive care, early disease diagnosis, therapy discovery, and personalized treatment protocols. It explores electronic medical and health records, clinical information systems, decision support systems, medical and biological imaging informatics, wearable systems, body area/sensor networks, and more. Integration-related topics like interoperability, evidence-based medicine, and secure patient data are also addressed.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书