选择性多探测器计算机断层扫描在经导管主动脉瓣植入术中的作用。

Marco Moscarelli, Philippe Pibarot, Nicolas Van Mieghem, Patrizio Lancellotti, Thomas Modine, Nicolo Piazza, Mani A Vannan, Giuseppe Tarantini, Adriana Zlahoda-Huzior, Lakshmi P Dasi, Khalil Fattouch
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引用次数: 0

摘要

经导管主动脉瓣置入术越来越多地用于年轻和低风险患者,将注意力转向长期的人工瓣膜耐久性。虽然经胸超声心动图仍然是随访的基础,但它主要反映整体血流动力学,可能无法检测植入后的早期结构或几何异常。小叶增厚减弱和小叶运动减少,统称为亚临床小叶血栓形成,代表可能先于明显瓣膜功能障碍的动态现象。越来越多的证据表明,假体的几何形状,包括扩张不足、椭圆形、关节错位、倾斜和植入深度,可能会改变新窦血流并促进血栓底物的形成。多检测器计算机断层扫描能够综合评估小叶形态,瓣膜周围血栓和假体几何形状,为血栓形成的机械决定因素提供见解。在这篇最新的综述中,我们研究了多模态成像在确定血栓性瓣膜表型中的作用,并提出了一个实用的成像框架,将超声心动图与选择性多探测器计算机断层扫描结合起来,以支持个体化tavi后的监测和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Selective Multidetector Computed Tomography After a Transcatheter Aortic Valve Implant.

Transcatheter aortic valve implants are increasingly performed in younger and lower-risk patients, shifting attention towards long-term prosthetic valve durability. Although transthoracic echocardiography remains the cornerstone of follow-up, it primarily reflects global haemodynamics and may not detect early structural or geometric abnormalities after the valve is implanted. Hypoattenuated leaflet thickening and reduced leaflet motion, collectively referred to as subclinical leaflet thrombosis, represent dynamic phenomena that may precede overt valve dysfunction. Growing evidence suggests that prosthesis geometry, including underexpansion, ellipticity, commissural misalignment, canting, and implant depth, may alter neo-sinus flow and promote thrombotic substrate formation. Multidetector computed tomography enables integrated assessment of leaflet morphology, perivalvular thrombus, and prosthetic geometry, providing insights into the mechanical determinants of thrombosis. In this state-of-the-art review, we examine the role of multimodality imaging in identifying thrombogenic valve phenotypes and propose a pragmatic imaging framework integrating echocardiography with selective multidetector computed tomography to support the surveillance and management of individualized post-transcatheter aortic valve implants.

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