{"title":"从1975年到2000年临床精神药理学的发展:个人视角。","authors":"Sheldon H Preskorn","doi":"10.1097/PRA.0000000000000930","DOIUrl":null,"url":null,"abstract":"<p><p>As I prepare to step down from my position as Psychopharmacology Columnist for the Journal of Psychiatric Practice after over 30 years in that role, it seemed appropriate to look back and discuss some major developments in psychopharmacology that have occurred over the course of the 50+ years of my career. To keep this narrative manageable in a column format, it is divided into 2 columns. Neither this column nor the next will cover everything-that would require a textbook. Instead, I will cover selected topics from a personal perspective. This column will principally focus on the first 25 years of my career and covers 5 main topics: therapeutic drug monitoring, which led to pharmacogenomics, studies in child and adolescent psychiatry, drug development research, neurobiology, and forensic psychiatry.</p>","PeriodicalId":16909,"journal":{"name":"Journal of Psychiatric Practice","volume":"32 3","pages":"125-129"},"PeriodicalIF":1.0000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Developments in Clinical Psychopharmacology From 1975 Through 2000: A Personal Perspective.\",\"authors\":\"Sheldon H Preskorn\",\"doi\":\"10.1097/PRA.0000000000000930\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>As I prepare to step down from my position as Psychopharmacology Columnist for the Journal of Psychiatric Practice after over 30 years in that role, it seemed appropriate to look back and discuss some major developments in psychopharmacology that have occurred over the course of the 50+ years of my career. To keep this narrative manageable in a column format, it is divided into 2 columns. Neither this column nor the next will cover everything-that would require a textbook. Instead, I will cover selected topics from a personal perspective. This column will principally focus on the first 25 years of my career and covers 5 main topics: therapeutic drug monitoring, which led to pharmacogenomics, studies in child and adolescent psychiatry, drug development research, neurobiology, and forensic psychiatry.</p>\",\"PeriodicalId\":16909,\"journal\":{\"name\":\"Journal of Psychiatric Practice\",\"volume\":\"32 3\",\"pages\":\"125-129\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2026-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Psychiatric Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/PRA.0000000000000930\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psychiatric Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/PRA.0000000000000930","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
摘要
当我准备从《精神病学实践杂志》(Journal of psychiatry Practice)的精神药理学专栏作家的位置上退下来时,回顾和讨论精神药理学在我50多年的职业生涯中发生的一些重大发展似乎是合适的。为了使这个叙述以专栏的形式易于管理,它被分为两栏。本专栏和下一篇专栏都不会涵盖所有内容——这需要一本教科书。相反,我将从个人角度介绍选定的主题。本专栏将主要关注我职业生涯的前25年,涵盖5个主要主题:治疗药物监测,这导致了药物基因组学,儿童和青少年精神病学研究,药物开发研究,神经生物学和法医精神病学。
Developments in Clinical Psychopharmacology From 1975 Through 2000: A Personal Perspective.
As I prepare to step down from my position as Psychopharmacology Columnist for the Journal of Psychiatric Practice after over 30 years in that role, it seemed appropriate to look back and discuss some major developments in psychopharmacology that have occurred over the course of the 50+ years of my career. To keep this narrative manageable in a column format, it is divided into 2 columns. Neither this column nor the next will cover everything-that would require a textbook. Instead, I will cover selected topics from a personal perspective. This column will principally focus on the first 25 years of my career and covers 5 main topics: therapeutic drug monitoring, which led to pharmacogenomics, studies in child and adolescent psychiatry, drug development research, neurobiology, and forensic psychiatry.
期刊介绍:
Journal of Psychiatric Practice® seizes the day with its emphasis on the three Rs — readability, reliability, and relevance. Featuring an eye-catching style, the journal combines clinically applicable reviews, case studies, and articles on treatment advances with practical and informative tips for treating patients. Mental health professionals will want access to this review journal — for sharpening their clinical skills, discovering the best in treatment, and navigating this rapidly changing field.
Journal of Psychiatric Practice combines clinically applicable reviews, case studies, and articles on treatment advances with informative "how to" tips for surviving in a managed care environment.