Benedikt Bauer , Marcel Mayrhofer , Maximilian Zarfl , Lars-Peter Kamolz , Hanna Luze , Sebastian Philipp Nischwitz
{"title":"10年无复发的高风险II期皮肤黑色素瘤自然病程:1例报告","authors":"Benedikt Bauer , Marcel Mayrhofer , Maximilian Zarfl , Lars-Peter Kamolz , Hanna Luze , Sebastian Philipp Nischwitz","doi":"10.1016/j.jpra.2025.11.029","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>pT4b melanoma of the skin, especially the nodular subtype with present ulceration, typically entails a poor prognosis with high risk for metastatic spread. The accuracy of classic risk prediction models lacks at times. When situated in the face, these malignancies can pose a specific challenge to reconstructive surgeons. Profound fears of cancer treatment further complicate the management of these cases.</div></div><div><h3>Case presentation</h3><div>We present a case of facial reconstruction in a 58-year-old female patient with a high-risk stage II melanoma with recurrence-free survival (RFS) despite an almost 10-year delay of surgical treatment due to existential fears.</div></div><div><h3>Conclusions</h3><div>The presented case provides several key takeaways. First, from a dermatological standpoint, clinicians must expect the unexpected and should look for explanations. Second, from a reconstructive view, complex cases are rarely linear—staged revisions, and setbacks are integral to surgical success. Finally, from a human perspective, sincere empathy, and emotional intelligence are indispensable.</div></div>","PeriodicalId":37996,"journal":{"name":"JPRAS Open","volume":"48 ","pages":"Pages 205-212"},"PeriodicalIF":1.8000,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A 10-year recurrence-free natural course of high-risk stage II cutaneous melanoma: A case report\",\"authors\":\"Benedikt Bauer , Marcel Mayrhofer , Maximilian Zarfl , Lars-Peter Kamolz , Hanna Luze , Sebastian Philipp Nischwitz\",\"doi\":\"10.1016/j.jpra.2025.11.029\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>pT4b melanoma of the skin, especially the nodular subtype with present ulceration, typically entails a poor prognosis with high risk for metastatic spread. The accuracy of classic risk prediction models lacks at times. When situated in the face, these malignancies can pose a specific challenge to reconstructive surgeons. Profound fears of cancer treatment further complicate the management of these cases.</div></div><div><h3>Case presentation</h3><div>We present a case of facial reconstruction in a 58-year-old female patient with a high-risk stage II melanoma with recurrence-free survival (RFS) despite an almost 10-year delay of surgical treatment due to existential fears.</div></div><div><h3>Conclusions</h3><div>The presented case provides several key takeaways. First, from a dermatological standpoint, clinicians must expect the unexpected and should look for explanations. Second, from a reconstructive view, complex cases are rarely linear—staged revisions, and setbacks are integral to surgical success. Finally, from a human perspective, sincere empathy, and emotional intelligence are indispensable.</div></div>\",\"PeriodicalId\":37996,\"journal\":{\"name\":\"JPRAS Open\",\"volume\":\"48 \",\"pages\":\"Pages 205-212\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2026-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JPRAS Open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352587825002670\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/11/21 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JPRAS Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352587825002670","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/11/21 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"SURGERY","Score":null,"Total":0}
A 10-year recurrence-free natural course of high-risk stage II cutaneous melanoma: A case report
Background
pT4b melanoma of the skin, especially the nodular subtype with present ulceration, typically entails a poor prognosis with high risk for metastatic spread. The accuracy of classic risk prediction models lacks at times. When situated in the face, these malignancies can pose a specific challenge to reconstructive surgeons. Profound fears of cancer treatment further complicate the management of these cases.
Case presentation
We present a case of facial reconstruction in a 58-year-old female patient with a high-risk stage II melanoma with recurrence-free survival (RFS) despite an almost 10-year delay of surgical treatment due to existential fears.
Conclusions
The presented case provides several key takeaways. First, from a dermatological standpoint, clinicians must expect the unexpected and should look for explanations. Second, from a reconstructive view, complex cases are rarely linear—staged revisions, and setbacks are integral to surgical success. Finally, from a human perspective, sincere empathy, and emotional intelligence are indispensable.
期刊介绍:
JPRAS Open is an international, open access journal dedicated to publishing case reports, short communications, and full-length articles. JPRAS Open will provide the most current source of information and references in plastic, reconstructive & aesthetic surgery. The Journal is based on the continued need to improve surgical care by providing highlights in general reconstructive surgery; cleft lip, palate and craniofacial surgery; head and neck surgery; skin cancer; breast surgery; hand surgery; lower limb trauma; burns; and aesthetic surgery. The Journal will provide authors with fast publication times.