磺胺和磺胺二甲氧嘧啶在慢性肾盂肾炎患者中的药代动力学

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology Pub Date : 1987-09-01

V I Bobrov, V A Briker, G A Glezer, V P Iakovlev

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引用次数: 0

摘要

慢性肾盂肾炎、肾小球滤过未受损、小管重吸收降低的患者中硫磺胺的消除加速。这是由于肾小管中硫的重吸收降低。磺胺二甲氧嘧啶在这些患者中的药代动力学没有明显改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Pharmacokinetics of sulfalene and sulfadimethoxine in chronic pyelonephritis patients].

Accelerated elimination of sulfalen was observed in patients with chronic pyelonephritis, unimpaired glomerular filtration and lowered tubular reabsorption. This was due to lowered sulfalen reabsorption in the kidney tubules. Sulfadimethoxine pharmacokinetics in such patients was not significantly changed.

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Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology

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