D Zauli, C Crespi, F Miserocchi, M Musiani, F B Bianchi, E Pisi
{"title":"慢性肝病中抗肌动蛋白抗体检测底物的不同细胞类型的比较","authors":"D Zauli, C Crespi, F Miserocchi, M Musiani, F B Bianchi, E Pisi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Human cultured fibroblasts and Raji and peripheral blood mononuclear cells have been compared as substrates for the immunofluorescent detection of antiactin microfilament antibodies in sera from chronic liver disease. Raji and mononuclear cells, which exhibit a rich microfilament network, proved to be the most sensitive substrates for this purpose. The clinical relevance of these findings in the diagnosis of \"autoimmune\" chronic liver disease is discussed.</p>","PeriodicalId":77705,"journal":{"name":"Diagnostic and clinical immunology","volume":"5 4","pages":"184-7"},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of various cell types as substrates for the detection of antiactin antibodies in chronic liver disease.\",\"authors\":\"D Zauli, C Crespi, F Miserocchi, M Musiani, F B Bianchi, E Pisi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Human cultured fibroblasts and Raji and peripheral blood mononuclear cells have been compared as substrates for the immunofluorescent detection of antiactin microfilament antibodies in sera from chronic liver disease. Raji and mononuclear cells, which exhibit a rich microfilament network, proved to be the most sensitive substrates for this purpose. The clinical relevance of these findings in the diagnosis of \\\"autoimmune\\\" chronic liver disease is discussed.</p>\",\"PeriodicalId\":77705,\"journal\":{\"name\":\"Diagnostic and clinical immunology\",\"volume\":\"5 4\",\"pages\":\"184-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic and clinical immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic and clinical immunology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of various cell types as substrates for the detection of antiactin antibodies in chronic liver disease.
Human cultured fibroblasts and Raji and peripheral blood mononuclear cells have been compared as substrates for the immunofluorescent detection of antiactin microfilament antibodies in sera from chronic liver disease. Raji and mononuclear cells, which exhibit a rich microfilament network, proved to be the most sensitive substrates for this purpose. The clinical relevance of these findings in the diagnosis of "autoimmune" chronic liver disease is discussed.
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