{"title":"[肌肉减少症的临床表现及病理生理基础]","authors":"Sumito Ogawa","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Age-related loss of skeletal muscle mass, strength and function is known as sarcopenia, and its diagnostic criteria is based on usual gait speed, grip strength, and skeletal muscle mass. Whereas underlying mechanisms of sarcopenia remains to be fully clarified, recent studies have suggested age-related changes in inflammatory status and humoral factors might contribute to the pathophysiology of sarcopenia and linkage between bone and muscle metabolism.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"26 12","pages":"1703-1708"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Clinical manifestation and pathophyisological bases of sarcopenia.]\",\"authors\":\"Sumito Ogawa\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Age-related loss of skeletal muscle mass, strength and function is known as sarcopenia, and its diagnostic criteria is based on usual gait speed, grip strength, and skeletal muscle mass. Whereas underlying mechanisms of sarcopenia remains to be fully clarified, recent studies have suggested age-related changes in inflammatory status and humoral factors might contribute to the pathophysiology of sarcopenia and linkage between bone and muscle metabolism.</p>\",\"PeriodicalId\":502100,\"journal\":{\"name\":\"Clinical calcium\",\"volume\":\"26 12\",\"pages\":\"1703-1708\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical calcium\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical calcium","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Clinical manifestation and pathophyisological bases of sarcopenia.]
Age-related loss of skeletal muscle mass, strength and function is known as sarcopenia, and its diagnostic criteria is based on usual gait speed, grip strength, and skeletal muscle mass. Whereas underlying mechanisms of sarcopenia remains to be fully clarified, recent studies have suggested age-related changes in inflammatory status and humoral factors might contribute to the pathophysiology of sarcopenia and linkage between bone and muscle metabolism.