NELA评分和其他变量在预测急诊剖腹手术后ICU入院需求中的应用

IF 1.2 4区 医学 Q3 ANESTHESIOLOGY
Ashleigh J Punch, Bradley A Wibrow, Angela Jacques, Amyleigh Hall, Siobhan N Delaney, Matthew H Anstey
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引用次数: 0

摘要

国家紧急剖腹手术审计(NELA)设计的术前风险评分和关键建议改善了紧急剖腹手术患者的预后。然而,高危患者推荐的常规重症监护/高依赖病房(ICU)入院在逻辑上并不总是可行的,需要预测模型来确定哪些患者将受益。我们对2018年至2023年在西澳大利亚三级医院接受急诊剖腹手术的患者进行了一项研究,以确定急诊剖腹手术后需要住院的相关因素,定义为需要血管加压剂输注、持续肾脏替代治疗或通气。在确定的1100例患者中,875例纳入初步分析。在多因素分析中,美国麻醉医师学会分级(P=0.017)和术中血清乳酸峰值浓度bbb2.0 mmol/L (P=0.038)是是否需要ICU治疗的独立预测因素。NELA评分增加与死亡率相关;但与ICU治疗需求无相关性(P=0.993)。虽然只有35.8%的高危患者入住ICU,但包括死亡率和意外入住ICU在内的不良结局没有明显增加,27.4%的入住ICU的患者未接受特异性治疗。本研究为开发急诊剖腹手术后ICU住院的新预测模型提供了基础,并提示常规择期住院可能不一定比其他NELA标准更有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of the NELA score and other variables in predicting the need for ICU admission post emergency laparotomy.

The preoperative risk score and key recommendations designed by the National Emergency Laparotomy Audit (NELA) have resulted in improved outcomes for patients undergoing emergency laparotomy. However, the recommended routine intensive care/high dependency unit (ICU) admission for high-risk patients is not always logistically possible and predictive models are needed to identify patients who will benefit. We conducted a study of patients undergoing emergency laparotomy at our tertiary hospital in Western Australia between 2018 and 2023 to identify factors that were associated with the need for ICU admission after emergency laparotomy, as defined by the requirement for a vasopressor infusion, continuous renal replacement therapy or ventilation. Of 1100 patients identified, 875 were included in the primary analysis. In multivariate analysis, the only independent predictive factors of the need for ICU therapies were the American Society of Anesthesiologists grade (P=0.017) and peak intraoperative serum lactate concentration >2 mmol/L (P=0.038). An increased NELA score was associated with mortality; however, it was not associated with the requirement for any ICU therapy (P=0.993). Although only 35.8% of high-risk patients were admitted to ICU, there was no apparent increase in adverse outcomes including mortality or unexpected ICU admission, and 27.4% of patients that were admitted to ICU received no specific therapies. This study provides a basis for the development of new predictive models for ICU admission post emergency laparotomy, and suggests the possibility that routine elective admission might not necessarily add value beyond that achieved by other NELA standards.

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来源期刊
CiteScore
2.70
自引率
13.30%
发文量
150
审稿时长
3 months
期刊介绍: Anaesthesia and Intensive Care is an international journal publishing timely, peer reviewed articles that have educational value and scientific merit for clinicians and researchers associated with anaesthesia, intensive care medicine, and pain medicine.
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