Nur Adlina Ruslan BSc, Hussam Abdeljabar Ahmad Mizher BSc, MSc, PhD, Nur Hannan Najihah Mohamad Tawpik BSc, Syahrir Zaini BSc, PhD
{"title":"手机应用干预改善2型糖尿病患者服药依从性的有效性：一项系统综述","authors":"Nur Adlina Ruslan BSc, Hussam Abdeljabar Ahmad Mizher BSc, MSc, PhD, Nur Hannan Najihah Mohamad Tawpik BSc, Syahrir Zaini BSc, PhD","doi":"10.1002/jppr.70028","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Aim</h3>\n \n <p>Type 2 diabetes mellitus (T2DM) is a global health concern, and medication non-adherence contributes to poor glycaemic control and complications. Mobile applications are a potential strategy to improve adherence, but their effectiveness remains uncertain. This systematic review evaluates the effectiveness of mobile applications interventions in improving medication adherence in patients with T2DM.</p>\n </section>\n \n <section>\n \n <h3> Data Sources</h3>\n \n <p>A comprehensive search of PubMed, Cochrane Library, and Scopus was conducted.</p>\n </section>\n \n <section>\n \n <h3> Study Selection</h3>\n \n <p>Studies included were English-language studies published in from 2013–2023. Study quality was assessed using the Mixed Method Appraisal Tool.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Seven clinical studies with 717 participants (median age 54.7 years) were included. All studies showed improvements in adherence, but only four reported statistically significant changes. Among these, three studies also showed significant reductions in haemoglobin A1c (HbA1c) levels, suggesting a positive clinical impact. The studies were generally of high quality.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Mobile applications appear to improve medication adherence in T2DM patients compared to traditional care. However, the specific application features that enhance adherence are unclear due to variations in study designs and small sample sizes. Future research should focus on identifying key applications characteristics, improving usability, and ensuring cost-effectiveness to optimize patient outcomes.</p>\n </section>\n </div>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"55 5","pages":"365-374"},"PeriodicalIF":1.0000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.70028","citationCount":"0","resultStr":"{\"title\":\"The effectiveness of mobile application interventions in improving medication adherence among patients with type 2 diabetes mellitus: a systematic review\",\"authors\":\"Nur Adlina Ruslan BSc, Hussam Abdeljabar Ahmad Mizher BSc, MSc, PhD, Nur Hannan Najihah Mohamad Tawpik BSc, Syahrir Zaini BSc, PhD\",\"doi\":\"10.1002/jppr.70028\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Aim</h3>\\n \\n <p>Type 2 diabetes mellitus (T2DM) is a global health concern, and medication non-adherence contributes to poor glycaemic control and complications. Mobile applications are a potential strategy to improve adherence, but their effectiveness remains uncertain. This systematic review evaluates the effectiveness of mobile applications interventions in improving medication adherence in patients with T2DM.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Data Sources</h3>\\n \\n <p>A comprehensive search of PubMed, Cochrane Library, and Scopus was conducted.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Study Selection</h3>\\n \\n <p>Studies included were English-language studies published in from 2013–2023. Study quality was assessed using the Mixed Method Appraisal Tool.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Seven clinical studies with 717 participants (median age 54.7 years) were included. All studies showed improvements in adherence, but only four reported statistically significant changes. Among these, three studies also showed significant reductions in haemoglobin A1c (HbA1c) levels, suggesting a positive clinical impact. The studies were generally of high quality.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Mobile applications appear to improve medication adherence in T2DM patients compared to traditional care. However, the specific application features that enhance adherence are unclear due to variations in study designs and small sample sizes. 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The effectiveness of mobile application interventions in improving medication adherence among patients with type 2 diabetes mellitus: a systematic review
Aim
Type 2 diabetes mellitus (T2DM) is a global health concern, and medication non-adherence contributes to poor glycaemic control and complications. Mobile applications are a potential strategy to improve adherence, but their effectiveness remains uncertain. This systematic review evaluates the effectiveness of mobile applications interventions in improving medication adherence in patients with T2DM.
Data Sources
A comprehensive search of PubMed, Cochrane Library, and Scopus was conducted.
Study Selection
Studies included were English-language studies published in from 2013–2023. Study quality was assessed using the Mixed Method Appraisal Tool.
Results
Seven clinical studies with 717 participants (median age 54.7 years) were included. All studies showed improvements in adherence, but only four reported statistically significant changes. Among these, three studies also showed significant reductions in haemoglobin A1c (HbA1c) levels, suggesting a positive clinical impact. The studies were generally of high quality.
Conclusion
Mobile applications appear to improve medication adherence in T2DM patients compared to traditional care. However, the specific application features that enhance adherence are unclear due to variations in study designs and small sample sizes. Future research should focus on identifying key applications characteristics, improving usability, and ensuring cost-effectiveness to optimize patient outcomes.
期刊介绍：
The purpose of this document is to describe the structure, function and operations of the Journal of Pharmacy Practice and Research, the official journal of the Society of Hospital Pharmacists of Australia (SHPA). It is owned, published by and copyrighted to SHPA. However, the Journal is to some extent unique within SHPA in that it ‘…has complete editorial freedom in terms of content and is not under the direction of the Society or its Council in such matters…’. This statement, originally based on a Role Statement for the Editor-in-Chief 1993, is also based on the definition of ‘editorial independence’ from the World Association of Medical Editors and adopted by the International Committee of Medical Journal Editors.
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