{"title":"RadGLO:胶质瘤放射学特征分析和预后建模的互动平台。","authors":"Kavita Kundal, K Divya Rani, Vinodini D, Neeraj Kumar, Rahul Kumar","doi":"10.1038/s41698-025-01124-z","DOIUrl":null,"url":null,"abstract":"<p><p>Radiomic features, quantitative descriptors of tumor shape, texture, and intensity derived from MRI serve as powerful non-invasive biomarkers for glioma characterization and prognosis. We present Radiology of Glioma (RadGLO), an interactive platform that leverages these features across multi-institutional datasets (TCGA, UCSF, UPENN) to support grade-wise analysis, gene correlation, and survival prediction. RadGLO integrates two in-house developed modules, RaSPr for risk stratification and TumorVQ for region-specific tumor volume quantification, which also supports user-uploaded MRI data. By enabling personalized prognosis and aiding treatment planning, RadGLO offers a valuable resource that is openly accessible at https://project.iith.ac.in/cgntlab/radglo/ .</p>","PeriodicalId":19433,"journal":{"name":"NPJ Precision Oncology","volume":"9 1","pages":"323"},"PeriodicalIF":6.8000,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521371/pdf/","citationCount":"0","resultStr":"{\"title\":\"RadGLO: an interactive platform for radiomic feature analysis and prognostic modeling in glioma.\",\"authors\":\"Kavita Kundal, K Divya Rani, Vinodini D, Neeraj Kumar, Rahul Kumar\",\"doi\":\"10.1038/s41698-025-01124-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Radiomic features, quantitative descriptors of tumor shape, texture, and intensity derived from MRI serve as powerful non-invasive biomarkers for glioma characterization and prognosis. We present Radiology of Glioma (RadGLO), an interactive platform that leverages these features across multi-institutional datasets (TCGA, UCSF, UPENN) to support grade-wise analysis, gene correlation, and survival prediction. RadGLO integrates two in-house developed modules, RaSPr for risk stratification and TumorVQ for region-specific tumor volume quantification, which also supports user-uploaded MRI data. By enabling personalized prognosis and aiding treatment planning, RadGLO offers a valuable resource that is openly accessible at https://project.iith.ac.in/cgntlab/radglo/ .</p>\",\"PeriodicalId\":19433,\"journal\":{\"name\":\"NPJ Precision Oncology\",\"volume\":\"9 1\",\"pages\":\"323\"},\"PeriodicalIF\":6.8000,\"publicationDate\":\"2025-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521371/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NPJ Precision Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41698-025-01124-z\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NPJ Precision Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41698-025-01124-z","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
RadGLO: an interactive platform for radiomic feature analysis and prognostic modeling in glioma.
Radiomic features, quantitative descriptors of tumor shape, texture, and intensity derived from MRI serve as powerful non-invasive biomarkers for glioma characterization and prognosis. We present Radiology of Glioma (RadGLO), an interactive platform that leverages these features across multi-institutional datasets (TCGA, UCSF, UPENN) to support grade-wise analysis, gene correlation, and survival prediction. RadGLO integrates two in-house developed modules, RaSPr for risk stratification and TumorVQ for region-specific tumor volume quantification, which also supports user-uploaded MRI data. By enabling personalized prognosis and aiding treatment planning, RadGLO offers a valuable resource that is openly accessible at https://project.iith.ac.in/cgntlab/radglo/ .
期刊介绍:
Online-only and open access, npj Precision Oncology is an international, peer-reviewed journal dedicated to showcasing cutting-edge scientific research in all facets of precision oncology, spanning from fundamental science to translational applications and clinical medicine.