腹主动脉瘤开放性修复手术延迟的预测因素和结果。

IF 3.6 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Xheni Konci, Boaz Laor, Robert J Doonan, Jason Bayne, Elie Girsowicz, Daniel Obrand, Oren Steinmetz, Kent MacKenzie, Heather Gill
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引用次数: 0

摘要

本研究的目的是表征选择性腹主动脉瘤(AAA)修复患者的手术等待时间,并确定与手术延迟相关的预测因素和不良后果。方法:回顾性分析两家医院中心2015-2025年间行开放式AAA修补术的患者。如果患者不打算接受选择性手术,则将其排除在研究之外。收集人口统计学、术前和术后数据,包括术前腹部计算机断层扫描(CT)扫描的时间间隔、手术同意、术前临床评估和手术日期。手术延迟定义为等待时间为80周,并从术前CT扫描和同意日期到手术当天进行评估。使用线性和逻辑回归分析来确定手术延迟的预测因素和不良的术后结果。结果:在468份回顾的病历中,298名患者被纳入研究。术前CT扫描至手术的中位时间为92天[IQR 59-142, n=247],同意手术的中位时间为61天[IQR 40-103, n=296]。患者在见血管外科医生后平均等待21天[IQR 10-33, n=289]进行术前用药评估。多变量logistic回归显示,从同意手术时间开始延迟手术的预测因子为脑血管疾病(OR 5.209, 95% CI 1.77, 19.26, p=0.006)、动脉瘤旁动脉瘤(OR 2.402, 95% CI 1.36, 4.35, p=0.003)和较小的AAA直径(OR 0.915, 95% CI 0.88, 0.95, p=7.1e-6)。只有较小的动脉瘤直径是延迟从CT扫描到手术的重要预测因子(OR 0.915, 95% CI 0.88, 0.95, p=9.22e-6)。在单变量(β=0.426, 95% CI 0.17, 0.69, p=0.001)和多变量线性回归(β=0.341, 95% CI 0.10, 0.58, p=0.006)中,手术时间延长与综合并发症指数的小幅但显著增加相关。等待期间隔破裂(n= 1,0.7%)和症状性AAAs (n= 5,1.7%)发生率较低。结论:在本综述中,手术延迟超过8周的患者有更高的术后并发症负担风险,应提前识别以确保及时干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictors and Outcomes of Surgical Delay in Open Abdominal Aortic Aneurysm Repair.

Introduction: The objectives of this study are to characterize surgical waiting times experienced by patients undergoing elective open abdominal aortic aneurysm (AAA) repair, as well as to identify predictors and adverse outcomes associated with surgical delay.

Methods: A retrospective chart review of patients undergoing open AAA repair between 2015-2025 was carried out in two hospital centres. Patients were excluded from the study if they were not planned to undergo an elective operation. Demographic, preoperative, and postoperative data were collected, including the time course between the preoperative abdominal computed tomography (CT) scan, procedure consent, preoperative clinic evaluation and surgery date. Surgical delay was defined as a wait time of >8 weeks and assessed from both the preoperative CT scan and consent date to the day of surgery. Linear and logistic regression analyses were used to identify predictors and adverse postoperative outcomes of surgical delay.

Results: Out of 468 charts reviewed, 298 patients were included in the study. The median time from the preoperative CT scan to surgery was 92 days [IQR 59-142, n=247], while the median time from the date of consent to surgery was 61 days [IQR 40-103, n=296]. Patients waited a median of 21 days [IQR 10-33, n=289] after seeing the vascular surgeon to be assessed by preoperative medicine. Multivariable logistic regression showed that predictors of surgical delay from the time of consent to surgery were cerebrovascular disease (OR 5.209, 95% CI 1.77, 19.26, p=0.006), juxtarenal aneurysms (OR 2.402, 95% CI 1.36, 4.35, p=0.003) and smaller AAA diameter (OR 0.915, 95% CI 0.88, 0.95, p=7.1e-6). Only smaller aneurysm diameter was a significant predictor of delay (OR 0.915, 95% CI 0.88, 0.95, p=9.22e-6) from the time of the CT scan to surgery. Prolonged time to surgery was associated with a small but significant increase in the comprehensive complication index in both univariable (β=0.426, 95% CI 0.17, 0.69, p=0.001) and multivariable linear regression (β=0.341, 95% CI 0.10, 0.58, p=0.006). The incidence of interval ruptures (n=1, 0.7%) and symptomatic AAAs (n=5, 1.7%) in the waiting period were low.

Conclusions: In this review, patients with prolonged surgical delay well beyond 8 weeks are at risk of experiencing a higher postoperative complication burden and should be identified pre-emptively to ensure timely intervention.

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来源期刊
CiteScore
7.70
自引率
18.60%
发文量
1469
审稿时长
54 days
期刊介绍: Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.
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