带有测量误差的协变量平衡。

IF 1.8 4区 医学 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Xialing Wen, Ying Yan
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引用次数: 0

摘要

近年来,越来越多的因果推理文献关注协变量平衡方法。这些方法通过平衡治疗组和对照组之间的协变量矩来消除观察到的混淆。协变量平衡的有效性依赖于一个隐含的假设,即所有协变量都是准确测量的,这在观察性研究中经常被违反。然而,测量误差对协变量平衡的影响尚不清楚,也没有充分平衡错测协变量的工作。在本文中,我们表明,天真地忽略测量误差反而增加了协变量不平衡的程度,并导致对治疗效果估计的偏差。然后,我们对现有的协变量平衡方法提出了一类测量误差校正策略。从理论上讲,我们证明这些策略成功地恢复了所有协变量的平衡,并消除了治疗效果估计的偏差。我们在模拟研究和实际数据分析中评估了所提出的校正方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Covariate Balancing With Measurement Error.

In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups. The validity of covariate balancing relies on an implicit assumption that all covariates are accurately measured, which is frequently violated in observational studies. Nevertheless, the impact of measurement error on covariate balancing is unclear, and there is no existing work on balancing mismeasured covariates adequately. In this article, we show that naively ignoring measurement error reversely increases the magnitude of covariate imbalance and induces bias to treatment effect estimation. We then propose a class of measurement error correction strategies for the existing covariate balancing methods. Theoretically, we show that these strategies successfully recover balance for all covariates and eliminate bias of treatment effect estimation. We assess the proposed correction methods in simulation studies and real data analysis.

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来源期刊
Statistics in Medicine
Statistics in Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.40
自引率
10.00%
发文量
334
审稿时长
2-4 weeks
期刊介绍: The journal aims to influence practice in medicine and its associated sciences through the publication of papers on statistical and other quantitative methods. Papers will explain new methods and demonstrate their application, preferably through a substantive, real, motivating example or a comprehensive evaluation based on an illustrative example. Alternatively, papers will report on case-studies where creative use or technical generalizations of established methodology is directed towards a substantive application. Reviews of, and tutorials on, general topics relevant to the application of statistics to medicine will also be published. The main criteria for publication are appropriateness of the statistical methods to a particular medical problem and clarity of exposition. Papers with primarily mathematical content will be excluded. The journal aims to enhance communication between statisticians, clinicians and medical researchers.
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