微极杰弗里流体在病变动脉中的磁控振荡流动:一种基于敏感性分析的非侵入性血栓治疗模型。

IF 6.3 2区 医学 Q1 BIOLOGY
P Vaidehi, J Sasikumar, Mustafa Turkyilmazoglu
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引用次数: 0

摘要

该研究通过结合磁影响下的微极性和杰弗里流体特征来解决病变动脉的复杂血流动力学问题,这对改进非侵入性诊断和治疗策略具有重要意义。主要目的是分析涡旋粘度、自旋梯度粘度、微惯性、流体弹性和磁场对狭窄动脉段振荡血流、微旋转和传热的影响。速度、微旋转和温度的控制方程是无量纲化的,使用Crank-Nicolson有限差分法求解,并通过正交阵列技术和蒙特卡罗模拟进行了额外的灵敏度和不确定性分析。结果表明,磁场会由于洛伦兹力阻尼而降低流速和微旋转,而流体弹性则会增强它们,传热对Eckert和Peclet数最为敏感,其中涡旋和自旋梯度粘度对耦合应力的影响最大。这些发现为预测磁辅助治疗中的流体和热行为提供了一个强大的计算框架,支持有针对性的临床应用,如磁疗、血管热疗和局部药物输送。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Magnetically controlled oscillatory flow of micropolar-Jeffrey fluid in a diseased artery: A sensitivity analysis-based model for non-invasive thrombosis treatment.

The study addresses the complex hemodynamics of diseased arteries by incorporating micropolar and Jeffrey fluid characteristics under magnetic influence, which is significant for improving non-invasive diagnostic and therapeutic strategies. The primary aim is to analyze the effect of vortex viscosity, spin gradient viscosity, micro-inertia, fluid elasticity and magnetic fields on oscillatory blood flow, microrotation and heat transfer in a stenosed arterial segment. The governing equations for velocity, microrotation and temperature are non-dimensionalized and solved using the Crank-Nicolson finite difference method, with additional sensitivity and uncertainty analyses performed via orthogonal array techniques and Monte Carlo simulations. Results reveal that magnetic fields reduce flow velocity and microrotation due to Lorentz force damping, while fluid elasticity enhances them and that heat transfer is most sensitive to the Eckert and Peclet numbers, with vortex and spin gradient viscosities having the strongest impact on couple stress. These findings provide a robust computational framework for predicting flow and thermal behaviors in magnetically assisted treatments, supporting targeted clinical applications such as magnetic therapy, vascular hyperthermia and localized drug delivery.

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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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