A review on wearable cardioverter-defibrillators in clinical practice for sudden cardiac death prevention and heart failure management.

Sudden cardiac death (SCD) remains a predominant mode of death in cardiovascular mortality. Despite advancements in guideline-recommended medical therapy (GRMT) and risk stratification, accurately identifying patients who would benefit most from implantable cardioverter-defibrillator (ICD) therapy over the long term remains a significant challenge. The wearable cardioverter-defibrillator (WCD) has emerged as a non-invasive bridge to either ICD implantation or recovery of left ventricular function. This expert review presents a comprehensive and up-to-date summary of clinical evidence on WCD use for SCD prevention and heart failure (HF) management. Specifically, it will address: 1) The concept and mechanism of the WCD. 2) Evidence from randomized and observational studies regarding efficacy, safety, and cost-effectiveness. 3) Integration of the WCD into HF management. 4) Knowledge gaps and priorities for future research.