同伴康复指导联系（RC-link）干预研究：住院患者酒精使用障碍康复的随机对照试验方案

IF 1.9 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Contemporary clinical trials Pub Date : 2025-10-07 DOI:10.1016/j.cct.2025.108097

Kaileigh A. Byrne , Irene Pericot-Valverde , Lesley A. Ross , Josephine Pittman , Olivia Murphy , Moonseong Heo , Alain H. Litwin

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引用次数: 0

摘要

背景：酒精使用障碍（AUD）可导致严重的身体健康并发症，包括戒断、胰腺炎和肝硬化，需要住院治疗。然而，很少有基于证据的康复支持干预措施在住院环境中实施，持续的康复率仍然很低。在出院后护理连续性方面弥合这一差距的一个潜在干预措施是与同伴康复指导（PRC）服务联系起来，这是一种社会心理护理模式，由经过培训、认证的康复专业人员指导他人完成康复之旅。目的：本研究旨在检验同伴康复辅导联系（RC-Link）干预对康复结果、医院使用率和成本效益的影响，并研究潜在的心理社会机制的改变。方法：RC-Link研究是一项多地点、前瞻性、两组随机对照试验，比较城市和农村地区6个月的康复结果和12个月的随访。AUD患者将被招募并随机分配到RC-Link干预组或在住院期间接受短暂一次性干预的对照组。RC-Link干预需要医院发起与PRC的联系，外加6个月的个性化支持。主要结果是酗酒天数和住院费用的变化。次要结局包括AUD缓解、生物心理社会功能、死亡率、医院使用率和呼气酒精含量。社会支持和自我效能感是大学生心理变化的预测机制。将通过纵向面板调查和生态瞬时评估来评估措施。结论：RC-Link研究将告知实施长期住院患者PRC - link是否能以经济有效的方式改善AUD恢复结果并降低医院利用率。

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The peer recovery coaching linkage (RC-link) intervention study: Protocol for a randomized controlled trial for alcohol use disorder recovery in the inpatient hospital setting

Background

Alcohol Use Disorder (AUD) can cause significant physical health complications, including withdrawal, pancreatitis, and cirrhosis, that require inpatient hospitalization. However, few evidence-based recovery support interventions have been implemented in inpatient settings, and sustained recovery rates remain low. One potential intervention to bridge this gap in post-discharge continuity of care is linkage to peer recovery coaching (PRC) services, a psychosocial model of care in which trained, certified professionals in recovery guide others through their recovery journey.

Objectives

This study seeks to test the Peer Recovery Coaching Linkage (RC-Link) intervention's impact on recovery outcomes, hospital utilization, and cost-effectiveness, as well as examine potential psychosocial mechanisms of change.

Methods

The RC-Link Study is a multi-site, prospective, two-arm randomized controlled trial that compares recovery outcomes in urban and rural settings over six months with a twelve-month follow-up. Participants with AUD will be recruited and randomized to either the RC-Link intervention or a control group receiving a brief, one-time intervention during hospitalization. The RC-Link intervention entails hospital-initiated linkage to a PRC plus six months of personalized support. The primary outcomes are changes in heavy drinking days and hospital costs. Secondary outcomes include AUD remission, biopsychosocial functioning, mortality, hospital utilization, and breath alcohol content. The predicted mechanisms of change are social support and self-efficacy. Measures will be assessed through longitudinal panel surveys and ecological momentary assessment.

Conclusion

The RC-Link Study will inform whether implementing of a long-term inpatient PRC linkage improves AUD recovery outcomes and reduces hospital utilization in a cost-effective manner.

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来源期刊

Contemporary clinical trials 医学-药学

CiteScore

3.70

自引率

4.50%

发文量

281

审稿时长

44 days

期刊介绍： Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.