{"title":"心脏MRI T2制图与心脏相获取和改进的运动致敏驱动平衡血抑制。","authors":"Ebtihal Raheem Hammood, Shapoor Shirani, Sahar Asl Fallah, Farzad Maleki, Sadegh Dehghani","doi":"10.1093/radadv/umae013","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) imaging relies on T<sub>2</sub> mapping to assess myocardial tissue properties. However, T<sub>2</sub> maps are subject to motion artifacts and signal interference, prompting exploration of techniques such as gradient-spin-echo (GraSE) sequences, heart phase acquisition, and dark blood (DB) imaging to improve image quality and reliability.</p><p><strong>Purpose: </strong>This prospective study evaluates the T<sub>2</sub> relaxation time (T<sub>2</sub>) variability and the image quality of T<sub>2</sub> maps obtained in end-systole and end-diastole with and without fat saturation (FS), using GraSE sequence in CMR imaging. Furthermore, improved motion-sensitized driven-equilibrium (iMSDE) was compared with double inversion recovery (DIR) as an alternative DB technique.</p><p><strong>Materials and methods: </strong>Five variants of the DB GraSE sequence were developed and performed on a 1.5 Tesla MRI scanner. Forty-four healthy volunteers prospectively underwent the following sequences: GraSE in end-diastole (GraSE-ED), GraSE-ED with FS (GraSE-ED-FS), GraSE in end-systole (GraSE-ES), GraSE-ES with FS (GraSE-ES-FS), and commercial GraSE-ED (GraSE-CO). Four GraSE variants utilized iMSDE technique, while GraSE-CO used DIR for blood suppression. T<sub>2</sub>, image quality, and visual artifacts were measured.</p><p><strong>Results: </strong>Ten volunteers were excluded due to image artifacts or missing datasets. Among the remaining 34 participants, the mean global T<sub>2</sub> was measured. No significant differences were seen among all variants (<i>P</i> > .05 for all comparisons). Intra- and inter-reader agreement of global T<sub>2</sub> values for all GraSE sequence were very good (<i>r</i> > 0.8 for both). Image quality was rated moderate or good for all variants of GraSE sequences. A lower incidence of artifacts was observed in end-systolic compared to end-diastolic imaging.</p><p><strong>Conclusion: </strong>All variants of GraSE sequence are highly reproducible and myocardial T<sub>2</sub> values did not significantly differ with heart phase. iMSDE is feasible as an alternative DB technique for T<sub>2</sub> mapping enabling acquisition in systole, which shows a lower incidence of artifacts compared to diastole.</p>","PeriodicalId":519940,"journal":{"name":"Radiology advances","volume":"1 2","pages":"umae013"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481697/pdf/","citationCount":"0","resultStr":"{\"title\":\"Cardiac MRI T<sub>2</sub> mapping with heart phase acquisition and improved motion-sensitized driven equilibrium blood suppression.\",\"authors\":\"Ebtihal Raheem Hammood, Shapoor Shirani, Sahar Asl Fallah, Farzad Maleki, Sadegh Dehghani\",\"doi\":\"10.1093/radadv/umae013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) imaging relies on T<sub>2</sub> mapping to assess myocardial tissue properties. However, T<sub>2</sub> maps are subject to motion artifacts and signal interference, prompting exploration of techniques such as gradient-spin-echo (GraSE) sequences, heart phase acquisition, and dark blood (DB) imaging to improve image quality and reliability.</p><p><strong>Purpose: </strong>This prospective study evaluates the T<sub>2</sub> relaxation time (T<sub>2</sub>) variability and the image quality of T<sub>2</sub> maps obtained in end-systole and end-diastole with and without fat saturation (FS), using GraSE sequence in CMR imaging. Furthermore, improved motion-sensitized driven-equilibrium (iMSDE) was compared with double inversion recovery (DIR) as an alternative DB technique.</p><p><strong>Materials and methods: </strong>Five variants of the DB GraSE sequence were developed and performed on a 1.5 Tesla MRI scanner. Forty-four healthy volunteers prospectively underwent the following sequences: GraSE in end-diastole (GraSE-ED), GraSE-ED with FS (GraSE-ED-FS), GraSE in end-systole (GraSE-ES), GraSE-ES with FS (GraSE-ES-FS), and commercial GraSE-ED (GraSE-CO). Four GraSE variants utilized iMSDE technique, while GraSE-CO used DIR for blood suppression. T<sub>2</sub>, image quality, and visual artifacts were measured.</p><p><strong>Results: </strong>Ten volunteers were excluded due to image artifacts or missing datasets. Among the remaining 34 participants, the mean global T<sub>2</sub> was measured. No significant differences were seen among all variants (<i>P</i> > .05 for all comparisons). Intra- and inter-reader agreement of global T<sub>2</sub> values for all GraSE sequence were very good (<i>r</i> > 0.8 for both). Image quality was rated moderate or good for all variants of GraSE sequences. A lower incidence of artifacts was observed in end-systolic compared to end-diastolic imaging.</p><p><strong>Conclusion: </strong>All variants of GraSE sequence are highly reproducible and myocardial T<sub>2</sub> values did not significantly differ with heart phase. iMSDE is feasible as an alternative DB technique for T<sub>2</sub> mapping enabling acquisition in systole, which shows a lower incidence of artifacts compared to diastole.</p>\",\"PeriodicalId\":519940,\"journal\":{\"name\":\"Radiology advances\",\"volume\":\"1 2\",\"pages\":\"umae013\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481697/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiology advances\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/radadv/umae013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology advances","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/radadv/umae013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景：心血管磁共振（CMR）成像依赖于T2定位来评估心肌组织特性。然而，T2图受到运动伪影和信号干扰的影响，促使人们探索梯度自旋回波（GraSE）序列、心脏相位采集和暗血（DB）成像等技术，以提高图像质量和可靠性。目的：本前瞻性研究评估收缩期末和舒张期末有脂肪饱和（FS）和无脂肪饱和（FS）时T2松弛时间（T2）变异性和T2图谱的图像质量，使用GraSE序列进行CMR成像。此外，将改进的运动敏感驱动平衡（iMSDE）与双反转恢复（DIR）作为备选DB技术进行了比较。材料和方法：开发了DB GraSE序列的五个变体，并在1.5特斯拉MRI扫描仪上进行了检测。44名健康志愿者前瞻性地接受了以下序列：舒张末期GraSE （GraSE- ed）、GraSE- ed与FS （GraSE- ed -FS）、收缩期末期GraSE （GraSE- es）、GraSE- es与FS （GraSE- es -FS）和商用GraSE- ed （GraSE- co）。四个GraSE变体使用iMSDE技术，而GraSE- co使用DIR进行血液抑制。测量T2、图像质量和视觉伪影。结果：10名志愿者因图像伪影或缺失数据集而被排除。在其余34名参与者中，测量全球平均T2。各变异间无显著差异（P < 0.05）。所有比较为05)。所有GraSE序列的全局T2值在读取器内和读取器间的一致性都非常好（两者均为r >.8）。所有GraSE序列的图像质量都被评为中等或良好。与舒张末期成像相比，收缩期末期的伪影发生率较低。结论：GraSE序列的所有变异具有高重复性，心肌T2值随心脏期无显著差异。iMSDE是一种可行的替代DB技术，可以在收缩期进行T2测绘，与舒张期相比，它显示出更低的伪影发生率。
Cardiac MRI T2 mapping with heart phase acquisition and improved motion-sensitized driven equilibrium blood suppression.
Background: Cardiovascular magnetic resonance (CMR) imaging relies on T2 mapping to assess myocardial tissue properties. However, T2 maps are subject to motion artifacts and signal interference, prompting exploration of techniques such as gradient-spin-echo (GraSE) sequences, heart phase acquisition, and dark blood (DB) imaging to improve image quality and reliability.
Purpose: This prospective study evaluates the T2 relaxation time (T2) variability and the image quality of T2 maps obtained in end-systole and end-diastole with and without fat saturation (FS), using GraSE sequence in CMR imaging. Furthermore, improved motion-sensitized driven-equilibrium (iMSDE) was compared with double inversion recovery (DIR) as an alternative DB technique.
Materials and methods: Five variants of the DB GraSE sequence were developed and performed on a 1.5 Tesla MRI scanner. Forty-four healthy volunteers prospectively underwent the following sequences: GraSE in end-diastole (GraSE-ED), GraSE-ED with FS (GraSE-ED-FS), GraSE in end-systole (GraSE-ES), GraSE-ES with FS (GraSE-ES-FS), and commercial GraSE-ED (GraSE-CO). Four GraSE variants utilized iMSDE technique, while GraSE-CO used DIR for blood suppression. T2, image quality, and visual artifacts were measured.
Results: Ten volunteers were excluded due to image artifacts or missing datasets. Among the remaining 34 participants, the mean global T2 was measured. No significant differences were seen among all variants (P > .05 for all comparisons). Intra- and inter-reader agreement of global T2 values for all GraSE sequence were very good (r > 0.8 for both). Image quality was rated moderate or good for all variants of GraSE sequences. A lower incidence of artifacts was observed in end-systolic compared to end-diastolic imaging.
Conclusion: All variants of GraSE sequence are highly reproducible and myocardial T2 values did not significantly differ with heart phase. iMSDE is feasible as an alternative DB technique for T2 mapping enabling acquisition in systole, which shows a lower incidence of artifacts compared to diastole.
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