Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières
{"title":"单倍相同干细胞移植解决镰状细胞性贫血患者室性心律失常和功能障碍:病例报告和讨论。","authors":"Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières","doi":"10.1002/jha2.70161","DOIUrl":null,"url":null,"abstract":"<p>A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.</p><p><b>Trial Registration</b>: The authors have confirmed clinical trial registration is not needed for this submission</p>","PeriodicalId":72883,"journal":{"name":"EJHaem","volume":"6 5","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498570/pdf/","citationCount":"0","resultStr":"{\"title\":\"Haplo-Identical Stem Cell Transplant Resolves Ventricular Arrhythmias and Dysfunction in a Sickle Cell Anemia Patient: Case Report and Discussion\",\"authors\":\"Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières\",\"doi\":\"10.1002/jha2.70161\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.</p><p><b>Trial Registration</b>: The authors have confirmed clinical trial registration is not needed for this submission</p>\",\"PeriodicalId\":72883,\"journal\":{\"name\":\"EJHaem\",\"volume\":\"6 5\",\"pages\":\"\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-10-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498570/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EJHaem\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jha2.70161\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EJHaem","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jha2.70161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Haplo-Identical Stem Cell Transplant Resolves Ventricular Arrhythmias and Dysfunction in a Sickle Cell Anemia Patient: Case Report and Discussion
A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.
Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission