单倍相同干细胞移植解决镰状细胞性贫血患者室性心律失常和功能障碍:病例报告和讨论。

IF 1.2
EJHaem Pub Date : 2025-10-06 DOI:10.1002/jha2.70161
Gonzalo de Luna, Isabelle Genty, Vincent Parinet, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Sihem Iles, Geneviève Derumeaux, Nicolas Lellouche, Thibaut Moulin, Laurent Boyer, Sébastien Maury, Pablo Bartolucci, Thomas d'Humières
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引用次数: 0

摘要

一名镰状细胞性贫血合并严重室性心律失常和左心室功能障碍的患者在单倍相同干细胞移植后实现了快速、完全的心脏恢复,这引发了对SCA心脏病理生理的质疑,并强调了根治性治疗后可逆心脏并发症的可能性。试验注册:作者已确认本次提交不需要临床试验注册。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Haplo-Identical Stem Cell Transplant Resolves Ventricular Arrhythmias and Dysfunction in a Sickle Cell Anemia Patient: Case Report and Discussion

Haplo-Identical Stem Cell Transplant Resolves Ventricular Arrhythmias and Dysfunction in a Sickle Cell Anemia Patient: Case Report and Discussion

A Sickle Cell Anemia patient with severe ventricular arrhythmia and left ventricular dysfunction achieved rapid, complete cardiac recovery after haplo-identical stem cell transplantation, raising questions about SCA cardiac pathophysiology and highlighting the potential for reversible cardiac complications following curative treatment.

Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission

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