创伤后应激障碍的见解如何为功能性神经障碍的治疗提供信息

IF 21.8 Q1 PSYCHOLOGY, MULTIDISCIPLINARY
Andrea Putica, James Agathos, Kim Felmingham
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引用次数: 0

摘要

功能性神经障碍(FND)和创伤后应激障碍(PTSD)表现出相当大的心理和神经生物学相似性,尽管临床表现不同。在这一观点中,我们综合了情绪加工和调节,内感受加工,自我评价和分离,生理应激反应和恐惧消退学习的共同中断的新兴研究。根据这些共性,我们提出了一种以跨诊断机制为重点的方法来治疗FND,并借鉴了PTSD干预的证据基础。具体来说,我们研究了长时间暴露疗法和统一的情绪障碍跨诊断治疗方案的潜力,以解决FND症状,特别是在有情绪调节困难和有病史的人群中。虽然需要严格的经验验证,但将神经科学的见解与临床实践相结合,应该为FND患者复杂的神经精神特征的研究和干预开辟道路。尽管功能性神经障碍对人们的生活产生了影响,但有效的治疗方法仍然难以捉摸。从这个角度来看,Putica等人确定了这种情况与创伤后应激障碍之间的共同特征,并提出了改善治疗结果的机制靶点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

How insights from posttraumatic stress disorder can inform treatment of functional neurological disorder

How insights from posttraumatic stress disorder can inform treatment of functional neurological disorder
Functional neurological disorder (FND) and posttraumatic stress disorder (PTSD) show considerable psychological and neurobiological parallels despite distinct clinical presentations. In this Perspective, we synthesize emerging research on shared disruptions in emotion processing and regulation, interoceptive processing, self-appraisal and dissociation, physiological stress responses and fear-extinction learning. From these commonalities, we propose a transdiagnostic mechanism-focused approach to FND treatment, drawing on the evidence base for PTSD interventions. Specifically, we examine the potential of prolonged exposure therapy and the unified protocol for transdiagnostic treatment of emotional disorders to address FND symptoms, particularly in people with emotion-regulation difficulties and histories of histories. Although rigorous empirical validation is needed, bridging neuroscientific insights with clinical practice should open up avenues for research and intervention in complex neuropsychiatric features in people with FND. Despite the impact of functional neurological disorder on people’s lives, effective treatments remain elusive. In this Perspective, Putica et al. identify features shared between this condition and posttraumatic stress disorder to propose mechanistic targets for improved treatment outcomes.
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CiteScore
9.30
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