{"title":"马来海松酸与非甾体抗炎药缀合物的合成","authors":"G. F. Vafina, A. I. Poptsov","doi":"10.1134/S1070428025602365","DOIUrl":null,"url":null,"abstract":"<p>New conjugates were synthesized by the reaction of acetylsalicylic acid chlorides, naproxen, ibuprofen, and ketoprofen with 2- and 6-aminomaleopimaric acid derivatives. The structures of the synthesized compounds were proven by IR and <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, mass spectrometry, and elemental analysis.</p>","PeriodicalId":766,"journal":{"name":"Russian Journal of Organic Chemistry","volume":"61 8","pages":"1451 - 1457"},"PeriodicalIF":0.9000,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of Conjugates of Maleopimaric Acid with Nonsteroidal Anti-inflammatory Drugs\",\"authors\":\"G. F. Vafina, A. I. Poptsov\",\"doi\":\"10.1134/S1070428025602365\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>New conjugates were synthesized by the reaction of acetylsalicylic acid chlorides, naproxen, ibuprofen, and ketoprofen with 2- and 6-aminomaleopimaric acid derivatives. The structures of the synthesized compounds were proven by IR and <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, mass spectrometry, and elemental analysis.</p>\",\"PeriodicalId\":766,\"journal\":{\"name\":\"Russian Journal of Organic Chemistry\",\"volume\":\"61 8\",\"pages\":\"1451 - 1457\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1070428025602365\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070428025602365","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Synthesis of Conjugates of Maleopimaric Acid with Nonsteroidal Anti-inflammatory Drugs
New conjugates were synthesized by the reaction of acetylsalicylic acid chlorides, naproxen, ibuprofen, and ketoprofen with 2- and 6-aminomaleopimaric acid derivatives. The structures of the synthesized compounds were proven by IR and 1H and 13C NMR spectroscopy, mass spectrometry, and elemental analysis.
期刊介绍:
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.