评估镇痛药和癌症疼痛管理的替代方法:一项横断面研究。

IF 0.9 4区 医学 Q4 ONCOLOGY
Syed Hassam Ali Sami
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引用次数: 0

摘要

疼痛在癌症中非常普遍,需要适当的评估和管理。评估对癌症疼痛管理尤其重要,有助于改善医院的镇痛处方和替代方法,提高癌症患者的生活质量。本研究的目的是评估止痛剂和癌症疼痛管理的替代方法,并将目前的处方做法与世卫组织疼痛管理指南进行比较。方法采用横断面研究方法,在伊斯兰堡PIMS进行。分析203例患者资料。记录患者的年龄、性别、诊断、疼痛强度、镇痛药和处方的替代方法。所有变量采用描述性统计进行汇总,变量间比较采用卡方检验。结果26 ~ 35岁患者居多(29%),血癌患者占76%。51%的患者疼痛强度为中等。弱阿片类药物(曲马多69%,可待因+扑热息痛68%)是处方最多的药物。没有使用强效阿片类药物。只有3%的患者接受了替代疗法(物理治疗、放疗)。约54%的处方符合世卫组织疼痛管理指南。大多数疼痛管理策略与世卫组织的镇痛阶梯不一致,特别是对于明显缺乏强效阿片类药物的严重疼痛病例。发现癌症分期、疼痛强度和使用的镇痛药类型之间存在显著关联
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of analgesics and alternative approaches in cancer pain management: A cross-sectional study.

BackgroundPain is highly prevalent in cancer and requires proper assessment and management. The evaluation is important particularly in cancer pain management, to make some improvement in prescribing analgesics and alternative approaches in the hospitals to enhance the quality of life of cancer patients.ObjectiveThe objective of this study was to assess analgesics and alternative approaches in cancer pain management and compare current prescribing practices with WHO guidelines for pain management.MethodsA cross-sectional study was conducted at PIMS, Islamabad. Data of 203 patients was analyzed. Patients' age, gender, diagnoses, pain intensity, analgesics, and alternative approaches prescribed, were recorded. All these variables were summarized using descriptive statistics and comparison between variables done by using Chi-square test.ResultMost patients were aged 26-35 years (29%), and 76% had blood cancer. Pain intensity was moderate in 51% of patients. Weak opioids (tramadol 69%, codeine + paracetamol 68%) were the most prescribed drugs. No strong opioids were used. Only 3% of patients received alternative therapies (physiotherapy, radiotherapy). About 54% of prescriptions were consistent with WHO pain management guidelines. The majority of pain management strategies did not align with WHO's analgesic ladder, particularly for severe pain cases, where strong opioids were noticeably absent. Significant associations were found between cancer stage, pain intensity, and type of analgesics used (p < 0.05).ConclusionThis study found that the pain in cancer patients at PIMS is often undertreated, with a heavy reliance on weak opioids and low use of strong opioids and alternative therapies. Limited use of strong opioids reflects systemic barriers including restrictive regulations, high costs, and limited availability. Improved access to opioids, guideline-based prescribing, and integration of palliative care are essential to ensure effective pain relief for cancer patients in Pakistan.

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来源期刊
CiteScore
2.70
自引率
7.70%
发文量
276
期刊介绍: Journal of Oncology Pharmacy Practice is a peer-reviewed scholarly journal dedicated to educating health professionals about providing pharmaceutical care to patients with cancer. It is the official publication of the International Society for Oncology Pharmacy Practitioners (ISOPP). Publishing pertinent case reports and consensus guidelines...
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