激光脱毛到抗逆转录病毒治疗:来自印度跨性别者以人为本护理模式的发现

IF 4.9 1区 医学 Q2 IMMUNOLOGY
Simran Shaikh, Parthasarathy Mugundu Ramien, Jade Bell, Kanchan Pawar, Allison M. McFall, Saya Okram, Ajay Enugu, Lakshmi Ganapathi, Maria Salvat Ballester, Viswanathan Arumugam, Rose Pollard Kaptchuk, Aditya Singh, Shantanu Kumar Purohit, Alex Keuroghlian, Kevin Ard, Shruti H. Mehta, Sukhvinder Kaur, Kenneth H. Mayer, Sunil Suhas Solomon
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引用次数: 0

摘要

印度的变性妇女(TGW)继续承受着不成比例的艾滋病毒负担,并在接受性别确认护理方面面临持续的社会、法律和结构性障碍。方法自2021年以来,我们在印度海得拉巴、浦那和塔那建立了三家“Mitr”(意为朋友)诊所,主要面向跨性别者,工作人员主要来自社区。Mitr诊所就地提供免费艾滋病毒检测和接触前预防,并与政府抗逆转录病毒治疗中心联系。他们还为性别确认激素治疗(GAHT)提供免费咨询,补贴激光脱毛和法律援助。使用汇总统计分析客户服务利用数据,以评估艾滋病毒和性别肯定服务的接受情况;使用逻辑回归检查HIV检测的相关因素。在一个地点进行的半结构化访谈用于了解艾滋病毒检测的障碍/促进因素。结果在2021年3月至2024年9月期间,共有5223个独立客户注册;中位年龄为26岁。大多数人(86%)自认为是TGW, 35%的人有交易性行为。大多数客户(70%)以前没有获得公共部门艾滋病毒服务。大多数人(75%)到Mitr诊所接受性别确认护理,包括激光脱毛(53%)、GAHT咨询(34%)和手术转诊(26%)。超过一半(62%)有资格接受艾滋病毒检测的客户接受了筛查,其中6%是新诊断的。进入Mitr诊所接受性别确认手术服务与HIV检测接收显著相关(aOR: 1.51; 95% CI: 1.02, 2.25)。社区工作人员提供的服务是促进艾滋病毒检测的重要因素,而对耻辱和信息披露的担忧是明显的障碍。在585名对PrEP感兴趣并符合条件的患者中,576名(98%)开始了PrEP, 378名(66%)在3个月时持续PrEP。在454名艾滋病毒感染者(新诊断或以前已知)中,392名(86%)开始了抗逆转录病毒治疗。截至2024年9月30日,233人(59%)仍在接受Mitr诊所服务并继续接受艾滋病毒护理;在156名有数据的患者中,病毒抑制率为98%。Mitr模型强调了协调项目和社区优先事项的重要性。性别确认护理的提供吸引了许多原本可能无法获得艾滋病毒服务的客户;事实上,激光脱毛是艾滋病毒检测、预防和抗逆转录病毒治疗的关键切入点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Laser hair removal to antiretrovirals: findings from a person-centred care model for transgender people in India

Laser hair removal to antiretrovirals: findings from a person-centred care model for transgender people in India

Introduction

Transgender women (TGW) in India continue to bear disproportionate HIV burden and face persistent social, legal and structural barriers to receive gender-affirming care.

Methods

Since 2021, we established three “Mitr” (meaning: friend) clinics in Hyderabad, Pune and Thane, India, for transgender people with staffing primarily from the community. Mitr clinics provide free HIV testing and pre-exposure prophylaxis (PrEP) on site with linkage to government antiretroviral therapy (ART) centres. They also provide free consultation for gender-affirming hormone therapy (GAHT), subsidized laser hair removal and legal assistance. Client service utilization data were analysed using summary statistics to evaluate uptake of HIV and gender-affirming services; correlates of HIV testing were examined using logistic regression. Semi-structured interviews conducted at one site were used to understand barriers/facilitators of HIV testing.

Results

A total of 5223 unique clients registered between March 2021 and September 2024; median age was 26 years. Most (86%) self-identified as TGW, and 35% reported transactional sex. Most clients (70%) had not previously accessed public sector HIV services. The majority (75%) accessed Mitr clinics for gender-affirming care, including laser hair removal (53%), GAHT consultations (34%) and surgical referral (26%). Over half (62%) of clients eligible for HIV testing underwent screening, of whom 6% were newly diagnosed. Accessing Mitr clinics for gender-affirming surgical services was significantly associated with HIV testing receipt (aOR: 1.51; 95% CI: 1.02, 2.25). Services provided by staff from the community were a prominent facilitator for HIV testing, while stigma and disclosure concerns were notable barriers. Among 585 clients interested in and eligible for PrEP, 576 (98%) initiated PrEP, and 378 (66%) were PrEP persistent at 3 months. Of 454 clients with HIV (newly diagnosed or previously known), 392 (86%) initiated ART. As of 30 September 2024, 233 (59%) were still receiving Mitr clinic services and retained in HIV care; viral suppression was 98% among the 156 clients with data.

Conclusions

The Mitr model highlights the importance of aligning programme and community priorities. The provision of gender-affirming care attracted many clients who might not otherwise have accessed HIV services; indeed, laser hair removal served as the key entry point to HIV testing, PrEP and ART.

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来源期刊
Journal of the International AIDS Society
Journal of the International AIDS Society IMMUNOLOGY-INFECTIOUS DISEASES
CiteScore
8.60
自引率
10.00%
发文量
186
审稿时长
>12 weeks
期刊介绍: The Journal of the International AIDS Society (JIAS) is a peer-reviewed and Open Access journal for the generation and dissemination of evidence from a wide range of disciplines: basic and biomedical sciences; behavioural sciences; epidemiology; clinical sciences; health economics and health policy; operations research and implementation sciences; and social sciences and humanities. Submission of HIV research carried out in low- and middle-income countries is strongly encouraged.
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