Yiwei Qiu, Yao Tang, Yixuan Li, Li Cheng, Xu Wang, Baofeng Du, Ruhai Bai
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Meta-analyses were performed using Review Manager 5.4 (Cochrane Collaboration). The primary outcomes included glycated hemoglobin (HbA1c), fasting blood glucose (FBG), and postprandial blood glucose (PBG).</p><p><strong>Results: </strong>Out of 6283 records screened, 44 RCTs involving 27,178 T2DM patients were included (16,972 in the intervention group and 10,206 in the control group). Pooled results showed that online health management interventions significantly improved HbA1c, FBG, PBG, systolic blood pressure, diastolic blood pressure, and waist circumference. Improvements were also observed in dietary behavior, physical activity, and self-efficacy. However, no significant effects were found on body weight, body mass index, or lipid metabolism parameters, including total cholesterol, triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. Subgroup analyses indicated that interventions delivered by physicians, those targeting individuals aged ≥ 60 years, and those using digital coaching for less than six months were more effective in glycemic control.</p><p><strong>Conclusion: </strong>Online health management interventions may effectively support glycemic and blood pressure control and self-management in T2DM patients. Nevertheless, additional research with larger sample sizes and more extended follow-up periods is justified due to the substantial heterogeneity and limitations across the included studies.</p>","PeriodicalId":94177,"journal":{"name":"Primary care diabetes","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of online health management on type 2 diabetes mellitus: A systematic review and meta-analysis.\",\"authors\":\"Yiwei Qiu, Yao Tang, Yixuan Li, Li Cheng, Xu Wang, Baofeng Du, Ruhai Bai\",\"doi\":\"10.1016/j.pcd.2025.08.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Online health management has been implemented to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). 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引用次数: 0
摘要
背景：在线健康管理已被用于改善2型糖尿病（T2DM）患者的血糖控制。本研究旨在通过系统回顾和荟萃分析来评估在线健康管理干预在管理2型糖尿病方面的有效性。方法：从2010年1月1日至2024年9月1日，对pubmed、Web of Science、Cochrane Library、Embase、中国知识基础设施和万方数据6个数据库进行综合检索。符合条件的研究包括诊断为T2DM的成年人（≥18岁）的随机对照试验（RCTs）。两名独立审稿人筛选了这些研究并评估了偏倚风险。meta分析采用Review Manager 5.4 （Cochrane Collaboration）进行。主要结局包括糖化血红蛋白（HbA1c）、空腹血糖（FBG）和餐后血糖（PBG）。结果：在筛选的6283份记录中，纳入44项随机对照试验，涉及27,178例T2DM患者（干预组16,972例，对照组10,206例）。综合结果显示，在线健康管理干预显著改善了HbA1c、FBG、PBG、收缩压、舒张压和腰围。在饮食行为、体育活动和自我效能方面也有改善。然而，没有发现对体重、体重指数或脂质代谢参数（包括总胆固醇、甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇）有显著影响。亚组分析表明，由医生提供的干预措施，针对年龄≥ 60岁的个体，以及使用数字指导少于6个月的干预措施在血糖控制方面更有效。结论：在线健康管理干预可有效支持T2DM患者血糖、血压控制和自我管理。然而，由于纳入研究的异质性和局限性，需要进行更大样本量和更长的随访期的额外研究。
The effect of online health management on type 2 diabetes mellitus: A systematic review and meta-analysis.
Background: Online health management has been implemented to improve glycemic control in patients with type 2 diabetes mellitus (T2DM). This study aims to evaluate the effectiveness of online health management interventions in managing T2DM through a systematic review and meta-analysis.
Methods: A comprehensive search was conducted in six databases-PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang Data-from January 1, 2010, to September 1, 2024. Eligible studies included randomized controlled trials (RCTs) involving adults (≥ 18 years) diagnosed with T2DM. Two independent reviewers screened the studies and assessed the risk of bias. Meta-analyses were performed using Review Manager 5.4 (Cochrane Collaboration). The primary outcomes included glycated hemoglobin (HbA1c), fasting blood glucose (FBG), and postprandial blood glucose (PBG).
Results: Out of 6283 records screened, 44 RCTs involving 27,178 T2DM patients were included (16,972 in the intervention group and 10,206 in the control group). Pooled results showed that online health management interventions significantly improved HbA1c, FBG, PBG, systolic blood pressure, diastolic blood pressure, and waist circumference. Improvements were also observed in dietary behavior, physical activity, and self-efficacy. However, no significant effects were found on body weight, body mass index, or lipid metabolism parameters, including total cholesterol, triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. Subgroup analyses indicated that interventions delivered by physicians, those targeting individuals aged ≥ 60 years, and those using digital coaching for less than six months were more effective in glycemic control.
Conclusion: Online health management interventions may effectively support glycemic and blood pressure control and self-management in T2DM patients. Nevertheless, additional research with larger sample sizes and more extended follow-up periods is justified due to the substantial heterogeneity and limitations across the included studies.
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