{"title":"近距离放射治疗前瞻性临床试验的文献计量学分析。","authors":"Alaattin Ozen, Canan Ozdemir, Ilknur Harmankaya, Mehmet Halici, Zeynep Sarikaya, Ezgi Melis Tufanyazici","doi":"10.5114/jcb.2025.153240","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Brachytherapy is a well-established modality in oncology, particularly for prostate and cervical cancers, offering precise radiation delivery while sparing healthy tissues. Despite its clinical benefits, the research trajectory of brachytherapy in clinical trials remains underexplored. This bibliometric analysis aimed to assess publication trends, research focus areas, and citation impact of prospective clinical trials on brachytherapy.</p><p><strong>Material and methods: </strong>A bibliometric analysis was conducted using Web of Science database. Clinical trials were identified with key words \"brachytherapy\" and \"prospective\", without time restrictions. Bibliometric parameters analyzed included year of publication, journal distribution, authorship, institutional and geographical contributions, citation metrics, and disease focus.</p><p><strong>Results: </strong>A total of 84 clinical trials published between 1982 and 2024 were analyzed. The United States was the leading contributor (44.0%). Prostate cancer was the most frequently studied malignancy (35.7%), followed by breast (15.5%) and gynecologic cancers (13.1%). The \"International Journal of Radiation Oncology, Biology, Physics\" published the most trials. Citation analysis showed significant differences among cancer types, with soft tissue sarcoma studies having the highest median citation count (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>While clinical trial research in brachytherapy has expanded over time, notable disparities in research intensity and citation impact exist among disease sites. Greater attention to underrepresented malignancies, along with sustained investment, interdisciplinary collaboration, and enhanced training, is needed to advance the role of brachytherapy in cancer care.</p>","PeriodicalId":51305,"journal":{"name":"Journal of Contemporary Brachytherapy","volume":"17 4","pages":"275-279"},"PeriodicalIF":1.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489538/pdf/","citationCount":"0","resultStr":"{\"title\":\"Bibliometric analysis of prospective clinical trials on brachytherapy.\",\"authors\":\"Alaattin Ozen, Canan Ozdemir, Ilknur Harmankaya, Mehmet Halici, Zeynep Sarikaya, Ezgi Melis Tufanyazici\",\"doi\":\"10.5114/jcb.2025.153240\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Brachytherapy is a well-established modality in oncology, particularly for prostate and cervical cancers, offering precise radiation delivery while sparing healthy tissues. Despite its clinical benefits, the research trajectory of brachytherapy in clinical trials remains underexplored. This bibliometric analysis aimed to assess publication trends, research focus areas, and citation impact of prospective clinical trials on brachytherapy.</p><p><strong>Material and methods: </strong>A bibliometric analysis was conducted using Web of Science database. Clinical trials were identified with key words \\\"brachytherapy\\\" and \\\"prospective\\\", without time restrictions. Bibliometric parameters analyzed included year of publication, journal distribution, authorship, institutional and geographical contributions, citation metrics, and disease focus.</p><p><strong>Results: </strong>A total of 84 clinical trials published between 1982 and 2024 were analyzed. The United States was the leading contributor (44.0%). Prostate cancer was the most frequently studied malignancy (35.7%), followed by breast (15.5%) and gynecologic cancers (13.1%). The \\\"International Journal of Radiation Oncology, Biology, Physics\\\" published the most trials. Citation analysis showed significant differences among cancer types, with soft tissue sarcoma studies having the highest median citation count (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>While clinical trial research in brachytherapy has expanded over time, notable disparities in research intensity and citation impact exist among disease sites. Greater attention to underrepresented malignancies, along with sustained investment, interdisciplinary collaboration, and enhanced training, is needed to advance the role of brachytherapy in cancer care.</p>\",\"PeriodicalId\":51305,\"journal\":{\"name\":\"Journal of Contemporary Brachytherapy\",\"volume\":\"17 4\",\"pages\":\"275-279\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489538/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Contemporary Brachytherapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5114/jcb.2025.153240\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/31 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Contemporary Brachytherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5114/jcb.2025.153240","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/31 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的：近距离放射治疗在肿瘤学中是一种成熟的治疗方式，特别是前列腺癌和宫颈癌，在保留健康组织的同时提供精确的放射输送。尽管其临床益处，近距离放射治疗在临床试验中的研究轨迹仍未得到充分探索。本文献计量学分析旨在评估近距离放射治疗前瞻性临床试验的发表趋势、研究重点领域和引用影响。材料与方法：利用Web of Science数据库进行文献计量学分析。临床试验以“近距离治疗”和“前瞻性”为关键词进行识别，没有时间限制。分析的文献计量参数包括出版年份、期刊分布、作者、机构和地理贡献、引文计量和疾病焦点。结果：对1982年至2024年间发表的84项临床试验进行分析。美国是最大的贡献者（44.0%）。前列腺癌是最常见的恶性肿瘤（35.7%），其次是乳腺癌（15.5%）和妇科癌症（13.1%）。《国际放射肿瘤学、生物学、物理学杂志》发表的试验最多。引用分析显示不同癌症类型之间存在显著差异，其中软组织肉瘤研究的中位引用数最高（p < 0.05）。结论：虽然近距离放射治疗的临床试验研究随着时间的推移而扩大，但不同疾病部位的研究强度和引用影响存在显著差异。需要更多地关注代表性不足的恶性肿瘤，以及持续的投资、跨学科合作和加强培训，以提高近距离放疗在癌症治疗中的作用。
Bibliometric analysis of prospective clinical trials on brachytherapy.
Purpose: Brachytherapy is a well-established modality in oncology, particularly for prostate and cervical cancers, offering precise radiation delivery while sparing healthy tissues. Despite its clinical benefits, the research trajectory of brachytherapy in clinical trials remains underexplored. This bibliometric analysis aimed to assess publication trends, research focus areas, and citation impact of prospective clinical trials on brachytherapy.
Material and methods: A bibliometric analysis was conducted using Web of Science database. Clinical trials were identified with key words "brachytherapy" and "prospective", without time restrictions. Bibliometric parameters analyzed included year of publication, journal distribution, authorship, institutional and geographical contributions, citation metrics, and disease focus.
Results: A total of 84 clinical trials published between 1982 and 2024 were analyzed. The United States was the leading contributor (44.0%). Prostate cancer was the most frequently studied malignancy (35.7%), followed by breast (15.5%) and gynecologic cancers (13.1%). The "International Journal of Radiation Oncology, Biology, Physics" published the most trials. Citation analysis showed significant differences among cancer types, with soft tissue sarcoma studies having the highest median citation count (p < 0.05).
Conclusions: While clinical trial research in brachytherapy has expanded over time, notable disparities in research intensity and citation impact exist among disease sites. Greater attention to underrepresented malignancies, along with sustained investment, interdisciplinary collaboration, and enhanced training, is needed to advance the role of brachytherapy in cancer care.
期刊介绍：
The “Journal of Contemporary Brachytherapy” is an international and multidisciplinary journal that will publish papers of original research as well as reviews of articles. Main subjects of the journal include: clinical brachytherapy, combined modality treatment, advances in radiobiology, hyperthermia and tumour biology, as well as physical aspects relevant to brachytherapy, particularly in the field of imaging, dosimetry and radiation therapy planning. Original contributions will include experimental studies of combined modality treatment, tumor sensitization and normal tissue protection, molecular radiation biology, and clinical investigations of cancer treatment in brachytherapy. Another field of interest will be the educational part of the journal.
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