Callie Marshall, Stephanie Diggs, Morgan Pfeiffer, Anna Gerst, Alexa Brumfiel, Zachary A Vesoulis
{"title":"心脏重症监护病房婴儿大脑近红外光谱准确度的种族差异。","authors":"Callie Marshall, Stephanie Diggs, Morgan Pfeiffer, Anna Gerst, Alexa Brumfiel, Zachary A Vesoulis","doi":"10.1055/a-2714-3293","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Pulse oximeters overestimate arterial oxygen saturations in black versus white adults, children, and infants. While race's impact on near-infrared spectroscopy (NIRS) accuracy is less studied, some adult research suggests decreased accuracy in black patients. This study investigates the effect of race on NIRS accuracy in infants in a cardiac intensive care unit (CICU).</p><p><strong>Study design: </strong>A retrospective chart review was conducted for infants admitted to St. Louis Children's Hospital CICU from 2017-2023. Bland-Altman plots, Pearson correlations, and mean biases were analyzed.</p><p><strong>Result: </strong>254 infants (13% Black, 87% White) provided 3,687 central venous oxygen saturation (ScvO<sub>2</sub>)-cerebral regional oxygen saturation (rScO<sub>2</sub>) pairs. Measurement bias was -3.2% in Black infants and +0.1% in White infants (p<0.01).</p><p><strong>Conclusion: </strong>Cerebral NIRS underestimates ScvO<sub>2</sub> in Black infants but maintains negligible measurement bias in White infants. This is the first study to assess race and NIRS accuracy in infants; the difference is statistically significant but not clinically relevant in most contexts.</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Racial Variation in Cerebral Near Infrared Spectroscopy Accuracy Among Infants in a Cardiac Intensive Care Unit.\",\"authors\":\"Callie Marshall, Stephanie Diggs, Morgan Pfeiffer, Anna Gerst, Alexa Brumfiel, Zachary A Vesoulis\",\"doi\":\"10.1055/a-2714-3293\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Pulse oximeters overestimate arterial oxygen saturations in black versus white adults, children, and infants. While race's impact on near-infrared spectroscopy (NIRS) accuracy is less studied, some adult research suggests decreased accuracy in black patients. This study investigates the effect of race on NIRS accuracy in infants in a cardiac intensive care unit (CICU).</p><p><strong>Study design: </strong>A retrospective chart review was conducted for infants admitted to St. Louis Children's Hospital CICU from 2017-2023. Bland-Altman plots, Pearson correlations, and mean biases were analyzed.</p><p><strong>Result: </strong>254 infants (13% Black, 87% White) provided 3,687 central venous oxygen saturation (ScvO<sub>2</sub>)-cerebral regional oxygen saturation (rScO<sub>2</sub>) pairs. Measurement bias was -3.2% in Black infants and +0.1% in White infants (p<0.01).</p><p><strong>Conclusion: </strong>Cerebral NIRS underestimates ScvO<sub>2</sub> in Black infants but maintains negligible measurement bias in White infants. This is the first study to assess race and NIRS accuracy in infants; the difference is statistically significant but not clinically relevant in most contexts.</p>\",\"PeriodicalId\":7584,\"journal\":{\"name\":\"American journal of perinatology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-10-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of perinatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2714-3293\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of perinatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-2714-3293","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Racial Variation in Cerebral Near Infrared Spectroscopy Accuracy Among Infants in a Cardiac Intensive Care Unit.
Objective: Pulse oximeters overestimate arterial oxygen saturations in black versus white adults, children, and infants. While race's impact on near-infrared spectroscopy (NIRS) accuracy is less studied, some adult research suggests decreased accuracy in black patients. This study investigates the effect of race on NIRS accuracy in infants in a cardiac intensive care unit (CICU).
Study design: A retrospective chart review was conducted for infants admitted to St. Louis Children's Hospital CICU from 2017-2023. Bland-Altman plots, Pearson correlations, and mean biases were analyzed.
Result: 254 infants (13% Black, 87% White) provided 3,687 central venous oxygen saturation (ScvO2)-cerebral regional oxygen saturation (rScO2) pairs. Measurement bias was -3.2% in Black infants and +0.1% in White infants (p<0.01).
Conclusion: Cerebral NIRS underestimates ScvO2 in Black infants but maintains negligible measurement bias in White infants. This is the first study to assess race and NIRS accuracy in infants; the difference is statistically significant but not clinically relevant in most contexts.
期刊介绍：
The American Journal of Perinatology is an international, peer-reviewed, and indexed journal publishing 14 issues a year dealing with original research and topical reviews. It is the definitive forum for specialists in obstetrics, neonatology, perinatology, and maternal/fetal medicine, with emphasis on bridging the different fields.
The focus is primarily on clinical and translational research, clinical and technical advances in diagnosis, monitoring, and treatment as well as evidence-based reviews. Topics of interest include epidemiology, diagnosis, prevention, and management of maternal, fetal, and neonatal diseases. Manuscripts on new technology, NICU set-ups, and nursing topics are published to provide a broad survey of important issues in this field.
All articles undergo rigorous peer review, with web-based submission, expedited turn-around, and availability of electronic publication.
The American Journal of Perinatology is accompanied by AJP Reports - an Open Access journal for case reports in neonatology and maternal/fetal medicine.
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