Žiga Godicelj, Jure Kastelic, Vesna Levašič, Zmago Krajnc, Andrej Moličnik, Igor Novak, Jakob Naranđa, Jan Zajc, Samo K Fokter
{"title":"多孔钽模数胫骨假体与骨水泥全膝关节置换术的中期生存率比较。","authors":"Žiga Godicelj, Jure Kastelic, Vesna Levašič, Zmago Krajnc, Andrej Moličnik, Igor Novak, Jakob Naranđa, Jan Zajc, Samo K Fokter","doi":"10.1080/17434440.2025.2569571","DOIUrl":null,"url":null,"abstract":"<p><strong>Background & objectives: </strong>Cementless total knee arthroplasties (TKAs) with porous tantalum tibial components were developed to improve fixation and reduce implant failure rates in younger, active patients. However, mid-term outcomes remain uncertain. This retrospective study compared survival rates of cementless TKAs with porous tantalum posterior-stabilized (PS) modular tibial components to cemented PS components from the same implant system, using revision for aseptic loosening as the endpoint.</p><p><strong>Materials and methods: </strong>From January 2017 to November 2021, 899 TKAs were performed at a single tertiary center for osteoarthritis. Of these, 645 (71.7%) were cemented and 254 (28.3%) cementless. Median BMI was similar in both groups (30.0 kg/m<sup>2</sup> vs 31.0 kg/m<sup>2</sup>; <i>p</i> = 0.814). Cementless recipients were younger (median 66.0 vs. 72.0 years; <i>p</i> < 0.001). Follow-up continued through 31 December 2023.</p><p><strong>Results: </strong>Seven-year survival was lower in the cementless group (97.1%, 95% CI 94.9-99.3) vs. cemented group (97.8%, 95% CI 96.6-99.0). Tibial component loosening led to 5 revisions in the cementless group vs. 2 revisions in the cemented group (<i>p</i> < 0.05). Two cementless cases involved tibial tray fractures. Overall, 86 patients (9.6%) died of unrelated causes.</p><p><strong>Conclusions: </strong>Cementless porous tantalum TKAs had inferior mid-term performance for aseptic loosening, prompting their discontinuation at our institution.</p>","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"1-9"},"PeriodicalIF":2.7000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of mid-term survival of uncemented total knee arthroplasties with modular tibial components made of porous tantalum vs. cemented total knee arthroplasties.\",\"authors\":\"Žiga Godicelj, Jure Kastelic, Vesna Levašič, Zmago Krajnc, Andrej Moličnik, Igor Novak, Jakob Naranđa, Jan Zajc, Samo K Fokter\",\"doi\":\"10.1080/17434440.2025.2569571\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background & objectives: </strong>Cementless total knee arthroplasties (TKAs) with porous tantalum tibial components were developed to improve fixation and reduce implant failure rates in younger, active patients. 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Tibial component loosening led to 5 revisions in the cementless group vs. 2 revisions in the cemented group (<i>p</i> < 0.05). Two cementless cases involved tibial tray fractures. 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引用次数: 0
摘要
背景与目的:采用多孔钽胫骨假体的无骨水泥全膝关节置换术(tka)用于改善年轻、活跃患者的固定和降低假体失败率。然而,中期结果仍然不确定。本回顾性研究比较了采用多孔钽后稳定(PS)模块胫骨组件的无骨水泥tka与采用同一种植体系统的骨水泥PS组件的生存率,并以无菌松动翻修为终点。材料和方法:2017年1月至2021年11月,在单一三级骨关节炎中心进行899例tka。其中645例(71.7%)骨水泥,254例(28.3%)无骨水泥。两组的中位BMI相似(30.0 kg/m2 vs 31.0 kg/m2; p = 0.814)。结果:无骨水泥组的7年生存率(97.1%,95% CI 94.9-99.3)低于骨水泥组(97.8%,95% CI 96.6-99.0)。胫骨假体松动导致无骨水泥组5次翻修,而骨水泥组2次翻修(p结论:无骨水泥多孔钽tka在无菌松动方面的中期表现较差,促使其在本机构停止使用。
Comparison of mid-term survival of uncemented total knee arthroplasties with modular tibial components made of porous tantalum vs. cemented total knee arthroplasties.
Background & objectives: Cementless total knee arthroplasties (TKAs) with porous tantalum tibial components were developed to improve fixation and reduce implant failure rates in younger, active patients. However, mid-term outcomes remain uncertain. This retrospective study compared survival rates of cementless TKAs with porous tantalum posterior-stabilized (PS) modular tibial components to cemented PS components from the same implant system, using revision for aseptic loosening as the endpoint.
Materials and methods: From January 2017 to November 2021, 899 TKAs were performed at a single tertiary center for osteoarthritis. Of these, 645 (71.7%) were cemented and 254 (28.3%) cementless. Median BMI was similar in both groups (30.0 kg/m2 vs 31.0 kg/m2; p = 0.814). Cementless recipients were younger (median 66.0 vs. 72.0 years; p < 0.001). Follow-up continued through 31 December 2023.
Results: Seven-year survival was lower in the cementless group (97.1%, 95% CI 94.9-99.3) vs. cemented group (97.8%, 95% CI 96.6-99.0). Tibial component loosening led to 5 revisions in the cementless group vs. 2 revisions in the cemented group (p < 0.05). Two cementless cases involved tibial tray fractures. Overall, 86 patients (9.6%) died of unrelated causes.
Conclusions: Cementless porous tantalum TKAs had inferior mid-term performance for aseptic loosening, prompting their discontinuation at our institution.