大网膜游离微血管淋巴结移植治疗淋巴水肿。

IF 0.7 4区 医学 Q4 SURGERY
Benedikt Fuchs, Sinan Mert, Tim Nürnberger, Petra Zimmermann, Irene Mesas Aranda, Riccardo Giunta, Paul S Wiggenhauser
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引用次数: 0

摘要

淋巴水肿是一种慢性进行性疾病,可作为原发性疾病发生,也可继发于淋巴损伤(如淋巴结切除术或放疗后)。保守治疗通常只能提供有限的缓解,因此手术方法,如血管化大网膜淋巴结转移(VOLT)越来越相关。我们报告了两例晚期继发性下肢淋巴水肿后淋巴结切除术。两例患者在淋巴显像和MRI上均表现出严重的淋巴运输功能障碍。使用伏特进行双显微手术淋巴结转移。网膜因其高淋巴结密度和淋巴管生成潜力而被选中,术中分割以重建腹股沟和小腿区域。此外,利用PubMed对网膜淋巴结转移治疗淋巴水肿的文献进行了系统回顾。在这两例中,术后评估证实移植物灌注充足,临床淋巴水肿症状改善。文献回顾显示有一致的证据表明,伏特治疗后肢体体积显著缩小,淋巴引流改善,蜂窝织炎发生率显著降低。VOLT是治疗难治性淋巴水肿的一种有效的手术选择,可以显著提高患者的生活质量。尽管结果令人鼓舞,但需要进一步标准化的前瞻性长期研究来验证其有效性和安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Free Microvascular Lymph Node Transplantation from the Omentum for the Treatment of Lymphoedema].

Lymphoedema is a chronic, progressive condition that may occur as a primary disorder or secondarily following lymphatic damage, such as after lymphadenectomy or radiotherapy. Conservative therapies often provide only limited relief, so that surgical approaches like vascularised omental lymph node transfer (VOLT) are increasingly relevant.We present two cases of advanced secondary lower-limb lymphoedema following lymphadenectomy. Both patients demonstrated severe lymphatic transport dysfunction on lymphoscintigraphy and MRI. A double microsurgical lymph node transfer using VOLT was performed in each case. The omentum, selected for its high lymph node density and lymphangiogenic potential, was divided intraoperatively to reconstruct both the groin and lower leg regions. In addition, a systematic literature review on omental lymph node transfer for lymphoedema was conducted using PubMed.In both cases, postoperative assessment confirmed adequate perfusion of the grafts and clinical improvement of lymphoedema symptoms. The literature review revealed consistent evidence of significant limb volume reduction, improved lymphatic drainage, and a marked decrease in the incidence of cellulitis following VOLT.VOLT is an effective surgical option for therapy-refractory lymphoedema and may substantially improve patient quality of life. Despite promising results, further standardised prospective long-term studies are required to validate its efficacy and safety.

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来源期刊
CiteScore
1.00
自引率
14.30%
发文量
116
审稿时长
6-12 weeks
期刊介绍: Konzentriertes Fachwissen aus Forschung und Praxis Das Zentralblatt für Chirurgie – alle Neuigkeiten aus der Allgemeinen, Viszeral-, Thorax- und Gefäßchirurgie.
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