{"title":"脑膜炎奈瑟菌所致孤立性动眼神经麻痹1例并文献复习。","authors":"Sadia Zafar, Hessa Al Delail, Mahmoud Ghanaim","doi":"10.1186/s12245-025-00980-7","DOIUrl":null,"url":null,"abstract":"<p><p>Bacterial meningitis remains a significant cause of morbidity and mortality worldwide, despite advances in prevention and treatment. Prompt diagnosis and appropriate management are crucial for optimal patient outcomes. This case report describes a 22-year-old Bangladeshi male who presented to the emergency department with headache, neck pain, vomiting, and left eye ptosis, ultimately diagnosed with Neisseria meningitidis meningitis. This case highlights the rare but significant complication of oculomotor nerve palsy associated with this infection. We also present a literature review discussing the incidence, pathophysiology, and clinical implications of cranial nerve involvement in bacterial meningitis, focusing on N. meningitidis, and explore the diagnostic challenges posed by overlapping clinical presentations of bacterial and tuberculous meningitis, particularly in resource-limited settings.</p>","PeriodicalId":13967,"journal":{"name":"International Journal of Emergency Medicine","volume":"18 1","pages":"188"},"PeriodicalIF":2.0000,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490151/pdf/","citationCount":"0","resultStr":"{\"title\":\"Isolated oculomotor nerve palsy in Neisseria meningitidis meningitis: a case report and literature review.\",\"authors\":\"Sadia Zafar, Hessa Al Delail, Mahmoud Ghanaim\",\"doi\":\"10.1186/s12245-025-00980-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Bacterial meningitis remains a significant cause of morbidity and mortality worldwide, despite advances in prevention and treatment. Prompt diagnosis and appropriate management are crucial for optimal patient outcomes. This case report describes a 22-year-old Bangladeshi male who presented to the emergency department with headache, neck pain, vomiting, and left eye ptosis, ultimately diagnosed with Neisseria meningitidis meningitis. This case highlights the rare but significant complication of oculomotor nerve palsy associated with this infection. We also present a literature review discussing the incidence, pathophysiology, and clinical implications of cranial nerve involvement in bacterial meningitis, focusing on N. meningitidis, and explore the diagnostic challenges posed by overlapping clinical presentations of bacterial and tuberculous meningitis, particularly in resource-limited settings.</p>\",\"PeriodicalId\":13967,\"journal\":{\"name\":\"International Journal of Emergency Medicine\",\"volume\":\"18 1\",\"pages\":\"188\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-10-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490151/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Emergency Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s12245-025-00980-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Emergency Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s12245-025-00980-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
Isolated oculomotor nerve palsy in Neisseria meningitidis meningitis: a case report and literature review.
Bacterial meningitis remains a significant cause of morbidity and mortality worldwide, despite advances in prevention and treatment. Prompt diagnosis and appropriate management are crucial for optimal patient outcomes. This case report describes a 22-year-old Bangladeshi male who presented to the emergency department with headache, neck pain, vomiting, and left eye ptosis, ultimately diagnosed with Neisseria meningitidis meningitis. This case highlights the rare but significant complication of oculomotor nerve palsy associated with this infection. We also present a literature review discussing the incidence, pathophysiology, and clinical implications of cranial nerve involvement in bacterial meningitis, focusing on N. meningitidis, and explore the diagnostic challenges posed by overlapping clinical presentations of bacterial and tuberculous meningitis, particularly in resource-limited settings.
期刊介绍:
The aim of the journal is to bring to light the various clinical advancements and research developments attained over the world and thus help the specialty forge ahead. It is directed towards physicians and medical personnel undergoing training or working within the field of Emergency Medicine. Medical students who are interested in pursuing a career in Emergency Medicine will also benefit from the journal. This is particularly useful for trainees in countries where the specialty is still in its infancy. Disciplines covered will include interesting clinical cases, the latest evidence-based practice and research developments in Emergency medicine including emergency pediatrics.