内耳靶向治疗的影响。

IF 4.8 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Frontiers in Pharmacology Pub Date : 2025-09-17 eCollection Date: 2025-01-01 DOI:10.3389/fphar.2025.1620679
Tony Bonilla, Jake DiFatta, Esperanza Bas Infante, Stefania Goncalves
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引用次数: 0

摘要

科学研究极大地推动了医疗保健的进步。一个值得注意的应用是精准医学,它旨在分析和理解疾病病理,为患者提供个性化的医疗治疗。靶向肿瘤学是精准医学的一个分支,专注于识别和靶向调节癌细胞的特定分子,从而最大限度地减少对健康细胞的伤害。针对癌症的不同类型的靶向治疗包括单克隆抗体和小分子。本文旨在概述这些靶向肿瘤学和非肿瘤学治疗对听力的影响。此外,包括免疫相关不良事件在内的副作用将被视为这类患者听力恶化的潜在原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The influence of targeted therapies in the inner ear.

Scientific research has significantly propelled advancements in healthcare. One notable application is precision medicine, which seeks to analyze and comprehend disease pathology to offer personalized medical treatments to patients. Targeted oncology, a branch of precision medicine, focuses on identifying and targeting specific molecules that regulate cancer cells, thereby minimizing harm to healthy cells. Different types of targeted therapy against cancer include monoclonal antibodies and small molecules. This manuscript intends to provide an overview of the influence of these targeted oncology and non-oncology therapies on hearing. Furthermore, side effects including immune-related adverse events will be reviewed as potential causes of hearing deterioration in this patient population.

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来源期刊
Frontiers in Pharmacology
Frontiers in Pharmacology PHARMACOLOGY & PHARMACY-
CiteScore
7.80
自引率
8.90%
发文量
5163
审稿时长
14 weeks
期刊介绍: Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy and toxicology. Field Chief Editor Heike Wulff at UC Davis is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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