胸椎硬膜内髓外孤立性纤维性肿瘤1例报告及文献复习。

Surgical neurology international Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI:10.25259/SNI_489_2025
Chinelo Onyiah, Stephen Jaffee, Nathan Esplin, Kymberly Gyure, Danyal Quraishi, Peter Zaki, Trent Kite, Justin Davanzo
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引用次数: 0

摘要

背景:孤立性纤维性肿瘤(SFTs)是一种罕见的间充质肿瘤,被认为起源于毛细血管周围(Zimmermann)细胞。它们最常见于内脏胸膜。这里,一个79岁的男性表现为脊髓病,归因于单独的T8硬膜内髓外SFT。病例描述:一名79岁男性,表现为进行性麻痹数月。胸椎磁共振成像显示T8位左侧偏心性硬膜内髓外肿块。手术时,病变紧密附着于脊髓;尽管如此,它还是被成功地全部移除了。术后,患者短暂经历双侧下肢麻木增加。然而,1年后,他完好无损,随访研究证实无残留/复发病变。值得注意的是,组织病理学和免疫化学检查证实了SFT的诊断,归类为CNS WHO 1级。结论:尽管硬膜内髓外SFTs极为罕见,但我们在T8水平遇到了这样的病变,并被大面积切除,术后无神经系统后遗症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thoracic intradural extramedullary solitary fibrous tumor: A case report and review of the literature.

Background: Solitary fibrous tumors (SFTs) are rare neoplasms of mesenchymal origin that is thought to arise from pericapillary (Zimmermann) cells. They most commonly occur in the visceral pleura. Here, a 79-year-old male presented with myelopathy attributed to a solitary T8 intradural extramedullary SFT.

Case description: A 79-year-old male presented with progressive paraparesis over several months. A magnetic resonance imaging of the thoracic spine revealed a left-sided, eccentric intradural extramedullary mass at the T8 level. At surgery, the lesion was densely adherent to the cord; nevertheless, it was successfully removed in toto. Postoperatively, the patient transiently experienced increased bilateral lower extremity numbness. However, 1 year later, he was intact and the follow-up studies confirmed no residual/recurrent lesion. Notably, the histopathology and immunochemistry examinations confirmed the diagnosis of a SFT, classified as CNS WHO Grade 1.

Conclusion: Although intradural extramedullary SFTs are exceedingly rare, we encountered such a lesion at the T8 level that was grossly removed without postoperative neurological sequelae.

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