{"title":"3型成骨不全患者后下小脑动脉瘤破裂继发蛛网膜下腔出血1例报告及主题回顾。","authors":"Segev Gabay, Ariel Agur, Oz Haim","doi":"10.25259/SNI_611_2025","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by collagen Type I deficiency, leading to bone fragility, skeletal deformities, and, less commonly, vascular abnormalities. Cerebrovascular complications in OI are rare. There are few reports of subarachnoid hemorrhage (SAH) secondary to ruptured aneurysms in OI patients, particularly involving the posterior circulation.</p><p><strong>Case description: </strong>We present a unique scenario of a long-term survivor, a female patient, with Type III OI who experienced a spontaneous SAH due to a ruptured posterior inferior cerebellar artery aneurysm.</p><p><strong>Conclusion: </strong>Given the patient's underlying OI, special neurosurgical and endovascular techniques were employed to ensure safe aneurysm coiling and cerebrospinal fluid diversion. We outline these challenges faced in the management of such a patient and provide a literature review to contextualize our findings.</p>","PeriodicalId":94217,"journal":{"name":"Surgical neurology international","volume":"16 ","pages":"342"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482725/pdf/","citationCount":"0","resultStr":"{\"title\":\"Subarachnoid hemorrhage secondary to ruptured posterior inferior cerebellar artery aneurysm in a patient with type 3 osteogenesis imperfecta: A case report and topic review.\",\"authors\":\"Segev Gabay, Ariel Agur, Oz Haim\",\"doi\":\"10.25259/SNI_611_2025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by collagen Type I deficiency, leading to bone fragility, skeletal deformities, and, less commonly, vascular abnormalities. Cerebrovascular complications in OI are rare. There are few reports of subarachnoid hemorrhage (SAH) secondary to ruptured aneurysms in OI patients, particularly involving the posterior circulation.</p><p><strong>Case description: </strong>We present a unique scenario of a long-term survivor, a female patient, with Type III OI who experienced a spontaneous SAH due to a ruptured posterior inferior cerebellar artery aneurysm.</p><p><strong>Conclusion: </strong>Given the patient's underlying OI, special neurosurgical and endovascular techniques were employed to ensure safe aneurysm coiling and cerebrospinal fluid diversion. We outline these challenges faced in the management of such a patient and provide a literature review to contextualize our findings.</p>\",\"PeriodicalId\":94217,\"journal\":{\"name\":\"Surgical neurology international\",\"volume\":\"16 \",\"pages\":\"342\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482725/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical neurology international\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/SNI_611_2025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical neurology international","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/SNI_611_2025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Subarachnoid hemorrhage secondary to ruptured posterior inferior cerebellar artery aneurysm in a patient with type 3 osteogenesis imperfecta: A case report and topic review.
Background: Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by collagen Type I deficiency, leading to bone fragility, skeletal deformities, and, less commonly, vascular abnormalities. Cerebrovascular complications in OI are rare. There are few reports of subarachnoid hemorrhage (SAH) secondary to ruptured aneurysms in OI patients, particularly involving the posterior circulation.
Case description: We present a unique scenario of a long-term survivor, a female patient, with Type III OI who experienced a spontaneous SAH due to a ruptured posterior inferior cerebellar artery aneurysm.
Conclusion: Given the patient's underlying OI, special neurosurgical and endovascular techniques were employed to ensure safe aneurysm coiling and cerebrospinal fluid diversion. We outline these challenges faced in the management of such a patient and provide a literature review to contextualize our findings.