{"title":"不规范的皮肤美白霜使用引起局部类固醇引起的皮炎和结节性痤疮。","authors":"Sumedha Rajendra Zade, Sameer Uttamrao Khasbage","doi":"10.1136/bcr-2025-267614","DOIUrl":null,"url":null,"abstract":"<p><p>A woman in her early 30s developed severe facial erythema, telangiectasia, burning sensation and progressive hyperpigmentation after 12 months of using an over-the-counter skin-lightening product labelled 'skin-lightening cream' purchased from a local beauty store. Laboratory analysis confirmed the presence of clobetasol propionate 0.05% w/w, which was not disclosed on the product label. Following discontinuation, she developed painful nodulocystic acne as a delayed complication. Treatment with topical calcineurin inhibitors, emollients, photoprotection and oral doxycycline resulted in partial improvement of erythema and telangiectasia, though acne management remained challenging. This case highlights the significant public health risks posed by unregulated cosmetic products containing undisclosed potent corticosteroids and emphasises the need for increased clinical vigilance and regulatory oversight.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 9","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unregulated skin-lightening cream use causing topical steroid-induced dermatitis and nodulocystic acne.\",\"authors\":\"Sumedha Rajendra Zade, Sameer Uttamrao Khasbage\",\"doi\":\"10.1136/bcr-2025-267614\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A woman in her early 30s developed severe facial erythema, telangiectasia, burning sensation and progressive hyperpigmentation after 12 months of using an over-the-counter skin-lightening product labelled 'skin-lightening cream' purchased from a local beauty store. Laboratory analysis confirmed the presence of clobetasol propionate 0.05% w/w, which was not disclosed on the product label. Following discontinuation, she developed painful nodulocystic acne as a delayed complication. Treatment with topical calcineurin inhibitors, emollients, photoprotection and oral doxycycline resulted in partial improvement of erythema and telangiectasia, though acne management remained challenging. This case highlights the significant public health risks posed by unregulated cosmetic products containing undisclosed potent corticosteroids and emphasises the need for increased clinical vigilance and regulatory oversight.</p>\",\"PeriodicalId\":9080,\"journal\":{\"name\":\"BMJ Case Reports\",\"volume\":\"18 9\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMJ Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/bcr-2025-267614\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bcr-2025-267614","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Unregulated skin-lightening cream use causing topical steroid-induced dermatitis and nodulocystic acne.
A woman in her early 30s developed severe facial erythema, telangiectasia, burning sensation and progressive hyperpigmentation after 12 months of using an over-the-counter skin-lightening product labelled 'skin-lightening cream' purchased from a local beauty store. Laboratory analysis confirmed the presence of clobetasol propionate 0.05% w/w, which was not disclosed on the product label. Following discontinuation, she developed painful nodulocystic acne as a delayed complication. Treatment with topical calcineurin inhibitors, emollients, photoprotection and oral doxycycline resulted in partial improvement of erythema and telangiectasia, though acne management remained challenging. This case highlights the significant public health risks posed by unregulated cosmetic products containing undisclosed potent corticosteroids and emphasises the need for increased clinical vigilance and regulatory oversight.
期刊介绍:
BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.